McCole Declan相关文献与解析，生知库 | 链接生命科学的每一步

Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses

肠道上皮细胞PTPN2通过免疫介导的抗菌反应限制病原菌的定植。

doi:10.1080/19490976.2025.2559029

Chatterjee, Pritha; Spalinger, Marianne R; Acevedo, Charly; Santos, Alina N; Gries, Casey M; Manz, Salomon M; Canale, Vinicius; Shawki, Ali; Sayoc-Becerra, Anica; Lei, Hillmin; Crawford, Meli'sa S; Eckmann, Lars; Borneman, James; McCole, Declan F

The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis.

PTPN2 rs1893217 IBD 风险等位基因通过 JAK-STAT-CEACAM6 轴增加 AIEC 侵袭的易感性

期刊:Gut Microbes

影响因子:11

doi:10.1080/19490976.2025.2526136

Chatterjee Pritha, Canale Vinicius, King Stephanie J, Shawki Ali, Lei Hillmin, Santos Alina N, Haddad Michael, Gries Casey, McGovern Dermot P B, Borneman James, McCole Declan F

Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene.

托法替尼可减轻由 PTPN2 基因中的 IBD 风险变异引起的 SARS-CoV-2 感染易感性增加

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2024.101447

Spalinger Marianne R, Sanati Golshid, Chatterjee Pritha, Hai Rong, Li Jiang, Santos Alina N, Nordgren Tara M, Tremblay Michel L, Eckmann Lars, Hanson Elaine, Scharl Michael, Wu Xiwei, Boland Brigid S, McCole Declan F

新冠

发表日期：2025

文献求助收藏

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice.

PTPN2 调节炎症性肠病患者体内铁处理蛋白的表达，并预防小鼠缺铁

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26073356

Lei Hillmin, Shawki Ali, Santos Alina N, Canale Vinicius, Manz Salomon, Crawford Meli'sa S, Chatterjee Pritha, Spalinger Marianne R, Scharl Michael, McCole Declan F

Respiratory Exposure to Agriculture Dust Extract Alters Gut Commensal Species and Key Metabolites in Mice

呼吸道暴露于农业粉尘提取物会改变小鼠肠道共生菌群及其关键代谢物

期刊:Journal of Applied Toxicology

影响因子:2.8

doi:10.1002/jat.4808

Crawford, Meli'sa S; Ulu, Arzu; Ramirez, Briana M; Santos, Alina N; Chatterjee, Pritha; Canale, Vinicius; Manz, Salomon; Lei, Hillmin; Soriano, Sarah Mae; Nordgren, Tara M; McCole, Declan F

Brewing a Cure: Engineering Yeast to Reduce Inflammation-Driven Tumors

酿造治愈良方：改造酵母以减少炎症驱动的肿瘤

期刊:Digestive Diseases and Sciences

影响因子:2.5

doi:10.1007/s10620-025-09194-6

Immunology/Inflammation

Yeast

发表日期：2025

文献求助收藏

Genome-Wide Interrogation of SARS-CoV-2 RNA-Protein Interactions Uncovers Hidden Regulatory Sites.

对 SARS-CoV-2 RNA-蛋白质相互作用进行全基因组分析，揭示隐藏的调控位点

期刊:

影响因子:

doi:10.1101/2025.05.26.656146

Xiang Joy S, Zhao Karen X, Tadri Laliv, Tamaru Kurt, Yee Brian A, Rothamel Katherine, Schmok Jonathan C, Mueller Jasmine R, Park Samuel S, Madrigal Assael A, McVicar Rachael N, Kwong Elizabeth M, Croker Ben A, Clark Alex E, Carlin Aaron F, Acevedo Charly, McCole Declan, O'Leary SeÃ¡n E, Hai Rong, Leibel Sandra L, Yeo Gene W

Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses.

肠道上皮细胞 PTPN2 通过免疫导向的抗菌反应限制病原菌的定植

期刊:

影响因子:

doi:10.1101/2024.09.24.614848

Chatterjee Pritha, Spalinger Marianne R, Acevedo Charly, Gries Casey M, Manz Salomon M, Canale Vinicius, Santos Alina N, Shawki Ali, Sayoc-Becerra Anica, Lei Hillmin, Crawford Meli'sa S, Eckmann Lars, Borneman James, McCole Declan F

The ClC-2 Chloride Channel Activator, Lubiprostone, Improves Intestinal Barrier Function in Biopsies from Crohn's Disease but Not Ulcerative Colitis Patients

ClC-2氯离子通道激活剂鲁比前列酮可改善克罗恩病患者肠道活检样本中的肠道屏障功能，但对溃疡性结肠炎患者无效。

期刊:Pharmaceutics

影响因子:5.5

doi:10.3390/pharmaceutics15030811

Park, Young Su; Kang, Sang Bum; Marchelletta, Ronald R; Penrose, Harrison M; Ruiter-Visser, Roos; Jung, Barbara; Docherty, Michael J; Boland, Brigid S; Sandborn, William J; McCole, Declan F

Goblet of fire: how Chlamydia ignites region-specific colitis by hijacking goblet cells

火之杯：衣原体如何通过劫持杯状细胞引发区域特异性结肠炎

Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses

肠道上皮细胞PTPN2通过免疫介导的抗菌反应限制病原菌的定植。

The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis.

PTPN2 rs1893217 IBD 风险等位基因通过 JAK-STAT-CEACAM6 轴增加 AIEC 侵袭的易感性

Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene.

托法替尼可减轻由 PTPN2 基因中的 IBD 风险变异引起的 SARS-CoV-2 感染易感性增加

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice.

PTPN2 调节炎症性肠病患者体内铁处理蛋白的表达，并预防小鼠缺铁

Respiratory Exposure to Agriculture Dust Extract Alters Gut Commensal Species and Key Metabolites in Mice

呼吸道暴露于农业粉尘提取物会改变小鼠肠道共生菌群及其关键代谢物

Brewing a Cure: Engineering Yeast to Reduce Inflammation-Driven Tumors

酿造治愈良方：改造酵母以减少炎症驱动的肿瘤

Genome-Wide Interrogation of SARS-CoV-2 RNA-Protein Interactions Uncovers Hidden Regulatory Sites.

对 SARS-CoV-2 RNA-蛋白质相互作用进行全基因组分析，揭示隐藏的调控位点

Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses.

肠道上皮细胞 PTPN2 通过免疫导向的抗菌反应限制病原菌的定植

The ClC-2 Chloride Channel Activator, Lubiprostone, Improves Intestinal Barrier Function in Biopsies from Crohn's Disease but Not Ulcerative Colitis Patients

ClC-2氯离子通道激活剂鲁比前列酮可改善克罗恩病患者肠道活检样本中的肠道屏障功能，但对溃疡性结肠炎患者无效。