Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription

在耐他莫昔芬的乳腺癌细胞中，雌激素受体α46表达降低，而其重新表达可抑制细胞增殖和雌激素受体α66调控的靶基因转录。