PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia.
PHF6 调节造血干细胞和祖细胞,其缺失与 TLX3 的表达协同作用,导致白血病
期刊:Blood
影响因子:23.1
doi:10.1182/blood-2018-07-860726
McRae Helen M, Garnham Alexandra L, Hu Yifang, Witkowski Matthew T, Corbett Mark A, Dixon Mathew P, May Rose E, Sheikh Bilal N, Chiang William, Kueh Andrew J, Nguyen Tan A, Man Kevin, Gloury Renee, Aubrey Brandon J, Policheni Antonia, Di Rago Ladina, Alexander Warren S, Gray Daniel H D, Strasser Andreas, Hawkins Edwin D, Wilcox Stephen, Gécz Jozef, Kallies Axel, McCormack Matthew P, Smyth Gordon K, Voss Anne K, Thomas Tim