日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of peripheral pain generators with sigma-1 receptor Positron Emission Tomography/Magnetic Resonance Imaging in complex regional pain syndrome: initial study in a prospective trial

利用σ-1受体正电子发射断层扫描/磁共振成像技术识别复杂区域疼痛综合征中的外周疼痛发生器:一项前瞻性试验的初步研究

Baal, Joe D; Ghimire, Prinska; Wagle, Sagar; Lewis, Monisha; Xu, Yingding; Tawfik, Vivianne L; Davidzon, Guido; McCurdy, Christopher R; Biswal, Sandip; Yoon, Daehyun

Physiologically Based Pharmacokinetic Model for Clinical Translation and Prediction of Drug Interaction of the Major Kratom Alkaloid, Mitragynine

基于生理的药代动力学模型用于临床转化和预测主要克拉托姆生物碱帽柱木碱的药物相互作用。

Chiang, Yi-Hua; Kanumuri, Siva Rama Raju; Berthold, Erin C; Kamble, Shyam H; Gour, Abhishek; Kuntz, Michelle A; Senetra, Alexandria S; Mukhopadhyay, Sushobhan; Lin, Zhoumeng; McCurdy, Christopher R; Sharma, Abhisheak

A chromosome-level Mitragyna parvifolia genome unveils spirooxindole alkaloid diversification and mitraphylline biosynthesis.

染色体水平的帽柱木基因组揭示了螺环吲哚生物碱的多样化和帽柱木碱的生物合成

Laforest Larissa C, Nguyen Tuan-Anh M, Matsumoto Gabriel Oliveira, Ramachandria Pavithra, Chanderbali Andre, Kanumuri Siva Rama Raju, Sharma Abhisheak, McCurdy Christopher R, Dang Thu-Thuy T, Nadakuduti Satya Swathi

Alkaloid biosynthesis in medicinal crop kratom (Mitragyna speciosa) varies with postharvest, genetic, and seasonal factors

药用作物克拉托姆(Mitragyna speciosa)中的生物碱生物合成受采后处理、遗传和季节因素的影响。

Zhang, Mengzi; Lyndon, Annabella; Kanumuri, Siva Rama Raju; Sharma, Abhisheak; Pearson, Brian J; McCurdy, Christopher R; Chen, Jianjun

Dual Opioid-Neuropeptide FF Small Molecule Ligands Demonstrate Analgesia with Reduced Tolerance Liabilities

双重阿片-神经肽FF小分子配体表现出镇痛作用,且耐受性降低

Mottinelli, Marco; Journigan, V Blair; Obeng, Samuel; Pallares, Victoria L C; Mѐsangeau, Christophe; Kapanda, Coco N; Cutler, Stephen J; Lambert, Janet A; Eans, Shainnel O; Ganno, Michelle L; Sheng, Wanhui; King, Tamara; Sharma, Abhisheak; Mollereau, Catherine; Avery, Bonnie A; McLaughlin, Jay P; McCurdy, Christopher R

Kratom (Mitragyna speciosa) use for self-management of pain: Insights from cross-sectional and ecological momentary assessment data

克拉托姆(Mitragyna speciosa)用于自我疼痛管理:来自横断面和生态瞬时评估数据的启示

Mun, Chung Jung; Panlilio, Leigh V; Dunn, Kelly E; Thrul, Johannes; McCurdy, Christopher R; Epstein, David H; Smith, Kirsten E

In Vitro Pharmacology of Mitragynine at α-Adrenoceptors

体外药理学研究表明,帽柱木碱对α-肾上腺素受体有作用

Chen, Yiming; Seto, Jordan; Obeng, Samuel; Mottinelli, Marco; Mukhopadhyay, Sushobhan; Tyagi, Richa; Hampson, Aidan J; McCurdy, Christopher R; McMahon, Lance R; Moniri, Nader H; Canal, Clinton E

Effects of cannabis smoke and oral Δ9THC on cognition in young adult and aged rats

大麻烟雾和口服Δ9THC对青年和老年大鼠认知能力的影响

Zequeira, Sabrina; Gazarov, Emely A; Güvenli, Alara A; Berthold, Erin C; Senetra, Alexandria S; Febo, Marcelo; Hiranita, Takato; McMahon, Lance R; Sharma, Abhisheak; McCurdy, Christopher R; Setlow, Barry; Bizon, Jennifer L

Increased Plasma Concentrations of 6-oxo-Methylphenidate in CES1 G134E Carriers Following a Single Oral Dose of Methylphenidate

单次口服哌甲酯后,CES1 G134E 携带者血浆中 6-氧代哌甲酯浓度升高

Zhang, Qingchen; Melchert, Philip W; Awad, Ahmed; McCurdy, Christopher R; Krone, Beth; Newcorn, Jeffrey; Froehlich, Tanya E; Stein, Mark A; Raeuscher, Josephine; Zhu, Hao-Jie; Markowitz, John S

Implications of Indolethylamine N-Methyltransferase (INMT) in Health and Disease: Biological Functions, Disease Associations, Inhibitors, and Analytical Approaches

吲哚乙胺N-甲基转移酶(INMT)在健康和疾病中的作用:生物学功能、疾病关联、抑制剂和分析方法

Abouheif, Seif; Awad, Ahmed; McCurdy, Christopher R