日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CRISPR/Cas9 Screens Implicate RARA and SPNS1 in Doxorubicin Cardiotoxicity

CRISPR/Cas9筛选表明RARA和SPNS1与阿霉素心脏毒性有关

McDermott-Roe, Chris; Lv, Wenjian; Shao, Yeng; Hoshino, Atsushi; Arany, Zoltan; Musunuru, Kiran

Mechano-growth factor E-domain modulates cardiac contractile function through 14-3-3 protein interactomes

机械生长因子 E 结构域通过 14-3-3 蛋白质相互作用组调节心脏收缩功能

Christopher Solís, Walter C Thompson, James R Peña, Christopher McDermott-Roe, Paulina Langa, Chad M Warren, Magdalena Chrzanowska, Beata M Wolska, R John Solaro, Pieter Detombe, Paul H Goldspink

BRCA1/2 Mutations and Cardiovascular Function in Breast Cancer Survivors

BRCA1/2 突变与乳腺癌幸存者的心血管功能

Demissei, Biniyam G; Lv, WenJian; Wilcox, Nicholas S; Sheline, Karyn; Smith, Amanda M; Sturgeon, Kathleen M; McDermott-Roe, Chris; Musunuru, Kiran; Lefebvre, Bénédicte; Domchek, Susan M; Shah, Payal; Ky, Bonnie

The ADP/ATP translocase drives mitophagy independent of nucleotide exchange

ADP/ATP 转位酶独立于核苷酸交换驱动线粒体自噬

Atsushi Hoshino #, Wei-Jia Wang #, Shogo Wada, Chris McDermott-Roe, Chantell S Evans, Bridget Gosis, Michael P Morley, Komal S Rathi, Jian Li, Kristina Li, Steven Yang, Meagan J McManus, Caitlyn Bowman, Prasanth Potluri, Michael Levin, Scott Damrauer, Douglas C Wallace, Erika L F Holzbaur, Zoltan Ar

Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants

基于基因组学的与肌联蛋白截断变异相关的心脏病评估

Haggerty, Christopher M; Damrauer, Scott M; Levin, Michael G; Birtwell, David; Carey, David J; Golden, Alicia M; Hartzel, Dustin N; Hu, Yirui; Judy, Renae; Kelly, Melissa A; Kember, Rachel L; Lester Kirchner, H; Leader, Joseph B; Liang, Lusha; McDermott-Roe, Chris; Babu, Apoorva; Morley, Michael; Nealy, Zachariah; Person, Thomas N; Pulenthiran, Arichanah; Small, Aeron; Smelser, Diane T; Stahl, Richard C; Sturm, Amy C; Williams, Heather; Baras, Aris; Margulies, Kenneth B; Cappola, Thomas P; Dewey, Frederick E; Verma, Anurag; Zhang, Xinyuang; Correa, Adolfo; Hall, Michael E; Wilson, James G; Ritchie, Marylyn D; Rader, Daniel J; Murray, Michael F; Fornwalt, Brandon K; Arany, Zoltan

Investigation of a dilated cardiomyopathy-associated variant in BAG3 using genome-edited iPSC-derived cardiomyocytes

使用基因组编辑的 iPSC 衍生心肌细胞研究 BAG3 中的扩张型心肌病相关变异

Chris McDermott-Roe, Wenjian Lv, Tania Maximova, Shogo Wada, John Bukowy, Maribel Marquez, Shuping Lai, Amarda Shehu, Ivor Benjamin, Aron Geurts, Kiran Musunuru

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development

ESRP1 突变导致听力损失,这是由于选择性剪接缺陷破坏了耳蜗发育

Alex M Rohacek, Thomas W Bebee, Richard K Tilton, Caleb M Radens, Chris McDermott-Roe, Natoya Peart, Maninder Kaur, Michael Zaykaner, Benjamin Cieply, Kiran Musunuru, Yoseph Barash, John A Germiller, Ian D Krantz, Russ P Carstens, Douglas J Epstein

Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection

通过基因共靶向和筛选实现iPSCs中高效精准的基因组编辑

Mitzelfelt, Katie A; McDermott-Roe, Chris; Grzybowski, Michael N; Marquez, Maribel; Kuo, Chieh-Ti; Riedel, Michael; Lai, Shuping; Choi, Melinda J; Kolander, Kurt D; Helbling, Daniel; Dimmock, David P; Battle, Michele A; Jou, Chuanchau J; Tristani-Firouzi, Martin; Verbsky, James W; Benjamin, Ivor J; Geurts, Aron M

Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function

全转录组共表达分析表明,LRRC2 是线粒体和心脏功能的一种新型介质。

McDermott-Roe, Chris; Leleu, Marion; Rowe, Glenn C; Palygin, Oleg; Bukowy, John D; Kuo, Judy; Rech, Monika; Hermans-Beijnsberger, Steffie; Schaefer, Sebastian; Adami, Eleonora; Creemers, Esther E; Heinig, Matthias; Schroen, Blanche; Arany, Zoltan; Petretto, Enrico; Geurts, Aron M

Intravital imaging of the kidney in a rat model of salt-sensitive hypertension

在盐敏感性高血压大鼠模型中对肾脏进行活体成像

Endres, Bradley T; Sandoval, Ruben M; Rhodes, George J; Campos-Bilderback, Silvia B; Kamocka, Malgorzata M; McDermott-Roe, Christopher; Staruschenko, Alexander; Molitoris, Bruce A; Geurts, Aron M; Palygin, Oleg