日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preclinical assessment of pharmacokinetics and anticonvulsant activity of CBDTech, a novel orally administered cannabidiol (CBD) formulation for seizure and epilepsy

CBDTech是一种新型口服大麻二酚(CBD)制剂,用于治疗癫痫和癫痫发作,本研究对其药代动力学和抗惊厥活性进行了临床前评估。

McDonald, Jacob D; Zhou, Feng; Kulpa, Justyna; Kuehl, Philip J

Effect of TRPV4 Antagonist GSK2798745 on Chlorine Gas-Induced Acute Lung Injury in a Swine Model

TRPV4拮抗剂GSK2798745对氯气诱导的猪急性肺损伤模型的影响

Vermillion, Meghan S; Saari, Nathan; Bray, Mathieu; Nelson, Andrew M; Bullard, Robert L; Rudolph, Karin; Gigliotti, Andrew P; Brendler, Jeffrey; Jantzi, Jacob; Kuehl, Philip J; McDonald, Jacob D; Burgert, Mark E; Weber, Waylon; Sucoloski, Scott; Behm, David J

Prenatal airborne polycyclic aromatic hydrocarbon exposure, altered regulation of peroxisome proliferator-activated receptor gamma (Ppar)γ, and links with mammary cancer

产前空气中多环芳烃暴露、过氧化物酶体增殖激活受体γ (PPARγ) 调控改变以及与乳腺癌的关联

Lichtiger, Lydia; Jezioro, Jacqueline; Rivera, Janelle; McDonald, Jacob D; Terry, Mary Beth; Sahay, Debashish; Miller, Rachel L

Composition of aerosols from thermal degradation of flavors used in ENDS and tobacco products

电子尼古丁传送系统和烟草制品中使用的香料热降解产生的气溶胶成分

Kuehl, Philip J; McDonald, Jacob D; Weber, Derek T; Khlystov, Andrey; Nystoriak, Matthew A; Conklin, Daniel J

Vehicular Particulate Matter (PM) Characteristics Impact Vascular Outcomes Following Inhalation

吸入后车辆颗粒物(PM)特性对血管结局的影响

Zychowski, Katherine E; Tyler, Christina R Steadman; Sanchez, Bethany; Harmon, Molly; Liu, June; Irshad, Hammad; McDonald, Jacob D; Bleske, Barry E; Campen, Matthew J

Disposition and metabolism of 2',2'"-Dithiobisbenzanilide in rodents following intravenous and oral administration and dermal application

2',2'"-二硫代双苯甲酰苯胺经静脉注射、口服和皮肤给药后在啮齿动物体内的分布和代谢

Garner, C Edwin; Wegerski, Christopher J; Doyle-Eisele, Melanie; McDonald, Jacob D; Sanders, J Michael; Moeller, Benjamin C; Waidyanatha, Suramya

Mixed Vehicle Emissions Induces Angiotensin II and Cerebral Microvascular Angiotensin Receptor Expression in C57Bl/6 Mice and Promotes Alterations in Integrity in a Blood-Brain Barrier Coculture Model

混合车辆排放物可诱导C57Bl/6小鼠脑微血管血管紧张素II和血管紧张素受体表达,并促进血脑屏障共培养模型完整性的改变。

Suwannasual, Usa; Lucero, JoAnn; Davis, Griffith; McDonald, Jacob D; Lund, Amie K

The pharmacokinetics of ketamine following intramuscular injection to F344 rats

氯胺酮肌注F344大鼠后的药代动力学研究

Moeller, Benjamin; Espelien, Brenna; Weber, Waylon; Kuehl, Philip; Doyle-Eisele, Melanie; Garner, C Edwin; McDonald, Jacob D; Garcia, Efrain; Raulli, Robert; Laney, Judith

Exposure to traffic-generated air pollutants mediates alterations in brain microvascular integrity in wildtype mice on a high-fat diet

暴露于交通产生的空气污染物会改变高脂饮食野生型小鼠的脑微血管完整性。

Suwannasual, Usa; Lucero, JoAnn; McDonald, Jacob D; Lund, Amie K

The role of the lectin-like oxLDL receptor (LOX-1) in traffic-generated air pollution exposure-mediated alteration of the brain microvasculature in Apolipoprotein (Apo) E knockout mice

在载脂蛋白E (ApoE) 敲除小鼠中,凝集素样氧化低密度脂蛋白受体 (LOX-1) 在交通产生的空气污染暴露介导的脑微血管改变中的作用

Lucero, JoAnn; Suwannasual, Usa; Herbert, Lindsay M; McDonald, Jacob D; Lund, Amie K