日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Treatment of Dystrophic mdx Mice with an ADAMTS-5 Specific Monoclonal Antibody Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles

使用 ADAMTS-5 特异性单克隆抗体治疗营养不良 mdx 小鼠可增加离体快速收缩后肢肌肉的体外强度

Alex B Addinsall, Leonard G Forgan, Natasha L McRae, Rhys W Kelly, Penny L McDonald, Bryony McNeill, Daniel R McCulloch, Nicole Stupka

Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance

主要无碱基核酸内切酶 (APE1) 在细胞活力和基因毒素抗性中的功能

McNeill, Daniel R; Whitaker, Amy M; Stark, Wesley J; Illuzzi, Jennifer L; McKinnon, Peter J; Freudenthal, Bret D; Wilson, David M 3rd

Genetic reduction of the extracellular matrix protein versican attenuates inflammatory cell infiltration and improves contractile function in dystrophic mdx diaphragm muscles

细胞外基质蛋白 versican 的遗传减少可减轻炎症细胞浸润并改善营养不良型 mdx 膈肌的收缩功能

Natasha L McRae, Alex B Addinsall, Kirsten F Howlett, Bryony McNeill, Daniel R McCulloch, Nicole Stupka

Tumor-associated APE1 variant exhibits reduced complementation efficiency but does not promote cancer cell phenotypes.

肿瘤相关的 APE1 变体表现出较低的互补效率,但不会促进癌细胞表型

Illuzzi Jennifer L, McNeill Daniel R, Bastian Paul, Brenerman Boris, Wersto Robert, Russell Helen R, Bunz Fred, McKinnon Peter J, Becker Kevin G, Wilson David M 3rd

XRCC1 haploinsufficiency in mice has little effect on aging, but adversely modifies exposure-dependent susceptibility

小鼠 XRCC1 单倍体不足对衰老影响甚微,但会对暴露依赖性易感性产生不利影响。

McNeill, Daniel R; Lin, Ping-Chang; Miller, Marshall G; Pistell, Paul J; de Souza-Pinto, Nadja C; Fishbein, Kenneth W; Spencer, Richard G; Liu, Yie; Pettan-Brewer, Christina; Ladiges, Warren C; Wilson, David M 3rd

Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites

APE1功能受损会增强细胞对临床相关烷化剂和抗代谢物的敏感性。

McNeill, Daniel R; Lam, Wing; DeWeese, Theodore L; Cheng, Yung-Chi; Wilson, David M 3rd

Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1

人脱嘌呤/脱嘧啶核酸内切酶APE1抑制剂的鉴定和表征

Simeonov, Anton; Kulkarni, Avanti; Dorjsuren, Dorjbal; Jadhav, Ajit; Shen, Min; McNeill, Daniel R; Austin, Christopher P; Wilson, David M 3rd

Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision

对人类 Ape1 的无碱基内切酶活性在其他底物上的表征,以及 ATP 和序列环境对 AP 位点切开的影响

Berquist, Brian R; McNeill, Daniel R; Wilson, David M 3rd

Inhibition of Ape1 nuclease activity by lead, iron, and cadmium

铅、铁和镉对 Ape1 核酸酶活性的抑制作用

McNeill, Daniel R; Narayana, Avinash; Wong, Heng-Kuan; Wilson, David M 3rd