日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Tissue Virus Microenvironment with Activated Stress Responses Underlies Durable SIV Persistence

组织病毒微环境激活应激反应是SIV持久存在的基础

Hope, Thomas J; Crentsil, Eliana U; Arif, Muhammad S; Thomas, Yanique; Zhang, Ellen; Thuruthiyil, Christopher T; Moriarty, Ryan V; Engelmann, Flora; Pascoe, Sean C; Hasson, Jenna M; Borrowman, Seth H; Shaaban, Maryam A; Allen, Edward J; Monette, Anne; Carias, Ann M; Ferrell, Douglas; Ouguirti, Nawal; Clerc, Isabelle; Hultquist, Judd F; D'Aquila, Richard T; McRaven, Michael D; Araínga, Mariluz; Villinger, Francois; Lorenzo-Redondo, Ramon

Blockade of de novo dNTP biosynthesis pathway delays HIV-1 early life cycle kinetics and dynamics.

阻断从头 dNTP 生物合成途径会延缓 HIV-1 早期生命周期的动力学和动态变化

Siddique Mohammad Anwar, McRaven Michael D, Arif Muhammad Shoaib, Allen Edward J, McKee Charia, Honne Shravya, Sultana Tahmina, Kim Baek, Carias Ann M, Mamede João I, Hope Thomas J

Vaginal microbiome dysbiosis and sexually transmitted infections correlate with concentrations of immunoglobulin isotypes in human cervicovaginal mucus: insights into HIV-1 transmission

阴道微生物群失调和性传播感染与人类宫颈阴道粘液中免疫球蛋白同种型的浓度相关:对 HIV-1 传播的启示

Akiso, Matrona M; Abook, Israel; Mureithi, Marianne W; Kombo, Janet; Koi, Print; Musando, Joel; Chirchir, Ruth J; McRaven, Michael D; Carias, Ann M; Joseph, Sarah; Anzala, Omu; Hope, Thomas J

Endocervix exhibits greater susceptibility to HIV-1 infection compared to ectocervix following ex vivo exposure to Transmitted/Founder HIV-1 variants

与宫颈外口相比,宫颈内口在体外暴露于传播/创始HIV-1变异株后,更容易感染HIV-1。

Langat, Robert; McRaven, Michael D; Lorenzo-Redondo, Ramon; Muhomah, Teresia; Carias, Ann M; Arif, Muhammad Shoaib; Akiso, Matrona Mbendo; Mureithi, Marianne; Anzala, Omu; Gilmour, Jill; Joseph, Sarah; Hope, Thomas J

PET/CT Targeted Tissue Sampling Reveals Intravenously Administered HGN194 IgG1 Affects HIV Distribution after Rectal Exposure

PET/CT靶向组织取样显示,静脉注射HGN194 IgG1会影响直肠暴露后HIV的分布

Taylor, Roslyn A; Xiao, Sixia; Carias, Ann M; McRaven, Michael D; Thakkar, Divya N; Araínga, Mariluz; Lorenzo-Redondo, Ramon; Allen, Edward J; Rogers, Kenneth A; Kumarapperuma, Sidath C; Gong, Siqi; Anderson, Meegan R; Thomas, Yanique; Madden, Patrick J; Corti, Davide; Cameroni, Elisabetta; Lanzavecchia, Antonio; Goins, Beth; Fox, Peter; Villinger, Francois J; Ruprecht, Ruth M; Hope, Thomas J

Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo

阻断TGF-β信号通路可重新激活体内HIV-1/SIV病毒库和免疫反应。

Samer, Sadia; Thomas, Yanique; Araínga, Mariluz; Carter, Crystal; Shirreff, Lisa M; Arif, Muhammad S; Avita, Juan M; Frank, Ines; McRaven, Michael D; Thuruthiyil, Christopher T; Heybeli, Veli B; Anderson, Meegan R; Owen, Benjamin; Gaisin, Arsen; Bose, Deepanwita; Simons, Lacy M; Hultquist, Judd F; Arthos, James; Cicala, Claudia; Sereti, Irini; Santangelo, Philip J; Lorenzo-Redondo, Ramon; Hope, Thomas J; Villinger, Francois J; Martinelli, Elena

Temporal and spatial characterization of HIV/SIV infection at anorectal mucosa using rhesus macaque rectal challenge model.

利用恒河猴直肠感染模型对肛门直肠黏膜上的 HIV/SIV 感染进行时空特征分析

Maric Danijela, Corbin Lisette, Greco Natalie, Lorenzo-Redondo Ramon, McRaven Michael D, Veazey Ronald S, Hope Thomas J

PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure

PET/CT靶向组织取样显示,病毒特异性dIgA可改变直肠暴露后HIV的分布和定位。

Taylor, Roslyn A; Xiao, Sixia; Carias, Ann M; McRaven, Michael D; Thakkar, Divya N; Araínga, Mariluz; Allen, Edward J; Rogers, Kenneth A; Kumarapperuma, Sidath C; Gong, Siqi; Fought, Angela J; Anderson, Meegan R; Thomas, Yanique; Schneider, Jeffrey R; Goins, Beth; Fox, Peter; Villinger, Francois J; Ruprecht, Ruth M; Hope, Thomas J

Localization of infection in neonatal rhesus macaques after oral viral challenge

新生恒河猴口服病毒攻击后感染部位的定位

Taylor, Roslyn A; McRaven, Michael D; Carias, Ann M; Anderson, Meegan R; Matias, Edgar; Araínga, Mariluz; Allen, Edward J; Rogers, Kenneth A; Gupta, Sandeep; Kulkarni, Viraj; Lakhashe, Samir; Lorenzo-Redondo, Ramon; Thomas, Yanique; Strickland, Amanda; Villinger, Francois J; Ruprecht, Ruth M; Hope, Thomas J

Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1

在慢性感染 HIV-1 的女性的血浆和母乳中分离出的多克隆 IgA 具有罕见的抗病毒功能

Tay, Matthew Zirui; Kunz, Erika L; Deal, Aaron; Zhang, Lu; Seaton, Kelly E; Rountree, Wes; Eudailey, Joshua A; Heptinstall, Jack; McRaven, Michael D; Matias, Edgar; McGuire, Erin; Yates, Nicole L; Perez, Lautaro G; Montefiori, David C; Overman, R Glenn; Hope, Thomas J; Shen, Xiaoying; Kalilani, Linda; Fouda, Genevieve G; Tomaras, Georgia D; Permar, Sallie R