日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Evidence that G-quadruplexes form in pathogenic fungi and represent promising antifungal targets

有证据表明,G-四链体在致病真菌中形成,并代表着有前景的抗真菌靶点。

Middleton, Georgie; Mahamud, Fuad O; Storer, Isabelle S R; Williams-Gunn, Abigail; Wostear, Finn; Abdolrasouli, Alireza; Barclay, Elaine; Bradford, Alice; Steward, Oliver; Schelenz, Silke; McColl, James; Lézé, Bertrand; van Rhijn, Norman; da Silva Dantas, Alessandra; Furukawa, Takanori; Warren, Derek; Waller, Zoë A E; Bidula, Stefan

The TECPR1:ATG5-ATG12 complex conjugates LC3/ATG8 to damaged lysosomes that expose luminal glycans in response to osmotic imbalance.

TECPR1:ATG5-ATG12 复合物将 LC3/ATG8 连接到受损的溶酶体上,从而在渗透压失衡时暴露腔内聚糖

Wang Yingxue, Jefferson Matthew, Ramos Maria, Whelband Matthew, Kreuzer Kristin, Khuu Grace, Lazarou Michael, Mccoll James, Lazenby James, Whitchurch Cynthia B, Verkade Paul, Mayer Ulrike, Wileman Thomas

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

抗体激动剂通过局部排除受体型蛋白酪氨酸磷酸酶来触发免疫受体信号传导。

Lippert Anna H, Paluch Christopher, Gaglioni Meike, Vuong Mai T, McColl James, Jenkins Edward, Fellermeyer Martin, Clarke Joseph, Sharma Sumana, Moreira da Silva Sara, Akkaya Billur, Anzilotti Consuelo, Morgan Sara H, Jessup Claire F, Körbel Markus, Gileadi Uzi, Leitner Judith, Knox Rachel, Chirifu Mami, Huo Jiandong, Yu Susan, Ashman Nicole, Lui Yuan, Wilkinson Ian, Attfield Kathrine E, Fugger Lars, Robertson Nathan J, Lynch Christopher J, Murray Lynne, Steinberger Peter, Santos Ana Mafalda, Lee Steven F, Cornall Richard J, Klenerman David, Davis Simon J

vLUME: 3D virtual reality for single-molecule localization microscopy

vLUME:用于单分子定位显微镜的3D虚拟现实

Spark, Alexander; Kitching, Alexandre; Esteban-Ferrer, Daniel; Handa, Anoushka; Carr, Alexander R; Needham, Lisa-Maria; Ponjavic, Aleks; Santos, Ana Mafalda; McColl, James; Leterrier, Christophe; Davis, Simon J; Henriques, Ricardo; Lee, Steven F

The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale

紧密接触的代价:纳米尺度下细胞接触能量分布的可视化

Kulenkampff, Klara; Lippert, Anna H; McColl, James; Santos, Ana Mafalda; Ponjavic, Aleks; Jenkins, Edward; Humphrey, Jane; Winkel, Alexander; Franze, Kristian; Lee, Steven F; Davis, Simon J; Klenerman, David

Capturing resting T cells: the perils of PLL

捕获静息T细胞:PLL的风险

Santos, Ana Mafalda; Ponjavic, Aleks; Fritzsche, Marco; Fernandes, Ricardo A; de la Serna, Jorge Bernardino; Wilcock, Martin J; Schneider, Falk; Urbančič, Iztok; McColl, James; Anzilotti, Consuelo; Ganzinger, Kristina A; Aßmann, Meike; Depoil, David; Cornall, Richard J; Dustin, Michael L; Klenerman, David; Davis, Simon J; Eggeling, Christian; Lee, Steven F

4D imaging reveals stage dependent random and directed cell motion during somite morphogenesis

4D成像揭示了体节形态发生过程中阶段依赖性的随机和定向细胞运动

McColl, James; Mok, Gi Fay; Lippert, Anna H; Ponjavic, Aleks; Muresan, Leila; Münsterberg, Andrea

Single-Molecule Light-Sheet Imaging of Suspended T Cells

悬浮T细胞的单分子光片成像

Ponjavic, Aleks; McColl, James; Carr, Alexander R; Santos, Ana Mafalda; Kulenkampff, Klara; Lippert, Anna; Davis, Simon J; Klenerman, David; Lee, Steven F

Single-molecule imaging reveals that small amyloid-β1-42 oligomers interact with the cellular prion protein (PrP(C))

单分子成像显示,小的淀粉样蛋白β1-42寡聚体与细胞朊病毒蛋白(PrP(C))相互作用。

Ganzinger, Kristina A; Narayan, Priyanka; Qamar, Seema S; Weimann, Laura; Ranasinghe, Rohan T; Aguzzi, Adriano; Dobson, Christopher M; McColl, James; St George-Hyslop, Peter; Klenerman, David

Single molecule characterization of the interactions between amyloid-β peptides and the membranes of hippocampal cells

利用单分子技术表征淀粉样β肽与海马细胞膜的相互作用

Narayan, Priyanka; Ganzinger, Kristina A; McColl, James; Weimann, Laura; Meehan, Sarah; Qamar, Seema; Carver, John A; Wilson, Mark R; St George-Hyslop, Peter; Dobson, Christopher M; Klenerman, David