日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ADAMTS1 Is Required for Ventral Abdominal Wall Closure

ADAMTS1是腹壁闭合所必需的

Opoku, Gabriel; Ikemura, Kentaro; Hatipoglu, Omer F; Ohtsuki, Takashi; Sato, Ikumi; Taniguchi, Hibiki; Sakamoto, Shino; Hasib, Farhana; Watanabe, Shogo; Mead, Timothy J; Apte, Suneel S; Hirohata, Satoshi

ADAMTS7, a target in atherosclerosis, cooperates with its homolog ADAMTS12 to protect against myxomatous valve degeneration.

ADAMTS7 是动脉粥样硬化的一个靶点,它与同源物 ADAMTS12 协同作用,防止粘液瘤样瓣膜退化

Mead Timothy J, Bhutada Sumit, Peruzzi Niccolò, Adegboye Janet, Seifert Deborah E, Cahill Elisabeth, Drinko Jeanne, Donnellan Eoin, Guggiliam Anu, Popovic Zoran, Griffin Brian, Tran-Lundmark Karin, Apte Suneel S

Localization, Proteolytic Processing, and Binding Partners of Versican Isoforms in Vascular Lesions of Pulmonary Arterial Hypertension.

肺动脉高压血管病变中 Versican 同工型的定位、蛋白水解加工和结合伙伴

Westöö Christian, Mutgan Ayse Ceren, van der Have Oscar, Mead Timothy J, Ahmed Salaheldin, Lampei Elna, Koch Christopher D, Norvik Christian, Aspberg Anders, Bech Martin, Peruzzi Niccolò, Brunnström Hans, Kwapiszewska Grazyna, Rådegran Göran, Apte Suneel S, Tran-Lundmark Karin

Loss of function variants in ADAMTS6 : Connective tissue, Heart defect, thoracic Aortic aneurysm and Neuro developmental Syndrome (CHANS)

ADAMTS6 功能缺失变异:结缔组织、心脏缺陷、胸主动脉瘤和神经发育综合征 (CHANS)

Huguet Herrero, Júlia; Arnaud, Pauline; Bibimbou, Angelique; Seifert, Deborah E; Mougin, Zakaria; Benarroch, Louise; Michot, Caroline; Capri, Yline; Ruaud, Lyse; Dupuis-Girod, Sophie; Guilhem, Alexandre; Beyer, Constance; Bajolle, Fanny; Milleron, Oliver; Jondeau, Guillaume; Hanna, Nadine; Reinhardt, Dieter P; Guo, Dong-Chuan; Milewicz, Dianna; Boileau, Catherine; Aubart, Mélodie; Mead, Timothy J; Le Goff, Carine

Generation of a conditional Adamts6 mouse allele reveals roles in lung maturation in addition to cardiac and musculoskeletal development

条件性 Adamts6 小鼠等位基因的构建揭示了其除心脏和肌肉骨骼发育外,在肺成熟中也发挥作用

Sirek, Jessica M; Rush, Elizabeth H; Darodkar, Aditi; Apte, Suneel S; Mead, Timothy J

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.

在特定时间窗口内,通过基因和药理学手段联合灭活紧密连接的 ADAMTS 蛋白酶,揭示了 versican 蛋白水解和 glypican-6 在心脏发育中的不同作用

Mead Timothy J, Bhutada Sumit, Foulcer Simon J, Peruzzi Niccolò, Nelson Courtney M, Seifert Deborah E, Larkin Jonathan, Tran-Lundmark Karin, Filmus Jorge, Apte Suneel S

Genetic insights into Tetralogy of Fallot: Oh MYH(6)

法洛四联症的遗传学见解:哦,MYH(6)

Mital, Rahul; Lozier, John S; Mead, Timothy J

Aggrecan accumulates at sites of increased pulmonary arterial pressure in idiopathic pulmonary arterial hypertension

在特发性肺动脉高压中,聚集蛋白聚糖会在肺动脉压力升高的部位积聚。

van der Have, Oscar; Mead, Timothy J; Westöö, Christian; Peruzzi, Niccolò; Mutgan, Ayse C; Norvik, Christian; Bech, Martin; Struglics, André; Hoetzenecker, Konrad; Brunnström, Hans; Westergren-Thorsson, Gunilla; Kwapiszewska, Grazyna; Apte, Suneel S; Tran-Lundmark, Karin

Proteolysis: a key post-translational modification regulating proteoglycans

蛋白水解:调控蛋白聚糖的关键翻译后修饰

Mead, Timothy J; Bhutada, Sumit; Martin, Daniel R; Apte, Suneel S

ADAMTS proteins in human disorders

ADAMTS蛋白在人类疾病中的作用

Mead, Timothy J; Apte, Suneel S