日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cortical Thickness Adaptive Response to Mechanical Loading Depends on Periosteal Position and Varies Linearly With Loading Magnitude

皮质厚度对机械载荷的适应性响应取决于骨膜位置,并与载荷强度呈线性关系。

Miller, Corey J; Trichilo, Silvia; Pickering, Edmund; Martelli, Saulo; Delisser, Peter; Meakin, Lee B; Pivonka, Peter

Murine Axial Compression Tibial Loading Model to Study Bone Mechanobiology: Implementing the Model and Reporting Results

利用小鼠轴向压缩胫骨载荷模型研究骨力学生物学:模型的建立和结果报告

Main, Russell P; Shefelbine, Sandra J; Meakin, Lee B; Silva, Matthew J; van der Meulen, Marjolein C H; Willie, Bettina M

Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2

机械应力介导的RANKL表达降低与RUNX2和BRD2相关。

Galea, Gabriel L; Paradise, Christopher R; Meakin, Lee B; Camilleri, Emily T; Taipaleenmaki, Hanna; Stein, Gary S; Lanyon, Lance E; Price, Joanna S; van Wijnen, Andre J; Dudakovic, Amel

Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle

衰老以及由此导致的骨骼负荷适应能力下降与细胞代谢、细胞-基质相互作用和细胞周期的转录组变化有关。

Galea, Gabriel L; Meakin, Lee B; Harris, Marie A; Delisser, Peter J; Lanyon, Lance E; Harris, Stephen E; Price, Joanna S

Quantification of Alterations in Cortical Bone Geometry Using Site Specificity Software in Mouse models of Aging and the Responses to Ovariectomy and Altered Loading

利用位点特异性软件量化衰老小鼠模型中皮质骨几何结构的变化以及卵巢切除术和负荷改变后的反应

Galea, Gabriel L; Hannuna, Sion; Meakin, Lee B; Delisser, Peter J; Lanyon, Lance E; Price, Joanna S

Exercise does not enhance aged bone's impaired response to artificial loading in C57Bl/6 mice.

运动并不能增强 C57Bl/6 小鼠衰老骨骼对人工负荷的受损反应

Meakin Lee B, Udeh Chinedu, Galea Gabriel L, Lanyon Lance E, Price Joanna S

The Contribution of Experimental in vivo Models to Understanding the Mechanisms of Adaptation to Mechanical Loading in Bone

体内实验模型对理解骨骼适应机械负荷机制的贡献

Meakin, Lee B; Price, Joanna S; Lanyon, Lance E

Deletion of P58(IPK), the Cellular Inhibitor of the Protein Kinases PKR and PERK, Causes Bone Changes and Joint Degeneration in Mice

P58(IPK)是蛋白激酶PKR和PERK的细胞抑制剂,其缺失会导致小鼠骨骼变化和关节退化。

Gilbert, Sophie J; Meakin, Lee B; Bonnet, Cleo S; Nowell, Mari A; Ladiges, Warren C; Morton, John; Duance, Victor C; Mason, Deborah J

Male mice housed in groups engage in frequent fighting and show a lower response to additional bone loading than females or individually housed males that do not fight.

群居的雄性小鼠经常打架,并且对额外的骨骼负荷的反应比雌性小鼠或单独饲养的雄性小鼠(不打架)要低

Meakin Lee B, Sugiyama Toshihiro, Galea Gabriel L, Browne William J, Lanyon Lance E, Price Joanna S

Spinal deformity in aged zebrafish is accompanied by degenerative changes to their vertebrae that resemble osteoarthritis

老年斑马鱼的脊柱畸形伴随着椎骨的退行性改变,类似于骨关节炎。

Hayes, Anthony J; Reynolds, Scott; Nowell, Mari A; Meakin, Lee B; Habicher, Judith; Ledin, Johan; Bashford, Andrew; Caterson, Bruce; Hammond, Chrissy L