Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages
由于ACE2水平较低，人类肺部对SARS-CoV-2的易感性有限，但病毒会诱导炎症巨噬细胞扩增。
期刊:European Respiratory Journal
影响因子:21
doi:10.1183/13993003.02725-2021
Hönzke, Katja; Obermayer, Benedikt; Mache, Christin; Fatykhova, Diana; Kessler, Mirjana; Dökel, Simon; Wyler, Emanuel; Baumgardt, Morris; Löwa, Anna; Hoffmann, Karen; Graff, Patrick; Schulze, Jessica; Mieth, Maren; Hellwig, Katharina; Demir, Zeynep; Biere, Barbara; Brunotte, Linda; Mecate-Zambrano, Angeles; Bushe, Judith; Dohmen, Melanie; Hinze, Christian; Elezkurtaj, Sefer; Tönnies, Mario; Bauer, Torsten T; Eggeling, Stephan; Tran, Hong-Linh; Schneider, Paul; Neudecker, Jens; Rückert, Jens C; Schmidt-Ott, Kai M; Busch, Jonas; Klauschen, Frederick; Horst, David; Radbruch, Helena; Radke, Josefine; Heppner, Frank; Corman, Victor M; Niemeyer, Daniela; Müller, Marcel A; Goffinet, Christine; Mothes, Ronja; Pascual-Reguant, Anna; Hauser, Anja Erika; Beule, Dieter; Landthaler, Markus; Ludwig, Stephan; Suttorp, Norbert; Witzenrath, Martin; Gruber, Achim D; Drosten, Christian; Sander, Leif-Erik; Wolff, Thorsten; Hippenstiel, Stefan; Hocke, Andreas C
巨噬细胞
SARS-CoV-2
炎症
炎症/感染
巨噬细胞
微生物学
Human
细胞生物学
ACE2
免疫/内分泌
