日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Soluble guanylate cyclase deficiency drives retinal ganglion cell neurodegeneration with age in female mice through disrupted oxidative metabolism.

可溶性鸟苷酸环化酶缺乏通过破坏氧化代谢,导致雌性小鼠视网膜神经节细胞随年龄增长而发生神经退行性变。

Bossardet Olivia L, Clark Kristin L, Wade Sequoia, Snyder Lydia A, Mecca Shane, Holden Joseph M, Almaoui Elio, Konety Rucha, Ghanem Ghazi O Bou, Korobkina Ekaterina D, Rex Tonia S, Wareham Lauren K

Inhibiting stearoyl-CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

抑制硬脂酰辅酶A去饱和酶可通过调节细胞应激、mTOR信号通路和DNA损伤反应来抑制骨转移性前列腺癌。

Wilson, Alexis; Herroon, Mackenzie K; Mecca, Shane; Garmo, Laimar C; Lindquist, Jacob; Rajendran, Shrila; Patrick, Steve M; Podgorski, Izabela

Targeting SCD in SCD-amplified prostate cancer inhibits growth in bone by modulating cellular stress, mTOR, and DNA damage pathways

靶向 SCD 可抑制 SCD 扩增型前列腺癌中 SCD 的骨内生长,其机制是通过调节细胞应激、mTOR 和 DNA 损伤通路。

Wilson, Alexis; Herroon, Mackenzie; Mecca, Shane; Garmo, Laimar; Lindquist, Jacob; Rajendran, Shrila; Patrick, Steve M; Podgorski, Izabela

Per- and polyfluorinated substances (PFAS) promote osteoclastogenesis and bone loss through PPARα activation.

全氟和多氟化合物(PFAS)通过PPARα激活促进破骨细胞生成和骨质流失

Garmo Laimar C, Herroon Mackenzie K, Mecca Shane, Wilson Alexis, Allen David R, Sayam Abu Sayed Mohammed, Specht Aaron J, Schlezinger Jennifer J, Petriello Michael C, Podgorski Izabela

Ru(II)-Photoactive Agents for Targeting ER Stress and Immunogenic Cell Death

用于靶向内质网应激和免疫原性细胞死亡的Ru(II)光敏剂

Denison, Madeline; Ullrich, Alexander; Herroon, Mackenzie K; Mecca, Shane; Turro, Claudia; Podgorski, Izabela; Gibson, Heather; Kodanko, Jeremy J