日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation.

白血病中发现的 SETD2 L1609P 突变会破坏甲基转移酶活性,降低组蛋白 H3K36 三甲基化。

Michail Christina, Berthelet Jérémy, Mechaly Ariel E, Bui Linh-Chi, Yang Haopeng, Cai Duo, Al Mahi Amira, Xie Aowei, Bisio Valeria, Sirri Valentina, Dupret Jean-Marie, Guidez Fabien, Xu Ximing, Joly Nicolas, Regad Leslie, Viguier Mireille, Deshayes Frédérique, Dulphy Nicolas, Green Michael R, Haouz Ahmed, Rodrigues Lima Fernando

Structural and functional characterization of CREB-binding protein (CREBBP) as a histone propionyltransferase.

CREB结合蛋白(CREBBP)作为组蛋白丙酰转移酶的结构和功能表征

Cui Guiling, Ley Marie, Mechaly Ariel E, Bui Linh-Chi, Michail Christina, Berthelet Jérémy, Dairou Julien, Yang Haopeng, Chevreux Guillaume, Moroy Gautier, Green Michael R, Haouz Ahmed, Rodrigues Lima Fernando

Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy

对导致极早发性自身免疫性肠病的人类蛋白酪氨酸磷酸酶PTPN2致病突变体(Cys216Gly)进行结构表征

Nian, Qing; Berthelet, Jérémy; Parlato, Marianna; Mechaly, Ariel E; Liu, Rongxing; Dupret, Jean-Marie; Cerf-Bensussan, Nadine; Haouz, Ahmed; Rodrigues Lima, Fernando

Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens

对当代梅毒株基因组的直接测序揭示了编码预测表面暴露抗原的基因中由重组驱动的多样性

Grillová, Linda; Oppelt, Jan; Mikalová, Lenka; Nováková, Markéta; Giacani, Lorenzo; Niesnerová, Anežka; Noda, Angel A; Mechaly, Ariel E; Pospíšilová, Petra; Čejková, Darina; Grange, Philippe A; Dupin, Nicolas; Strnadel, Radim; Chen, Marcus; Denham, Ian; Arora, Natasha; Picardeau, Mathieu; Weston, Christopher; Forsyth, R Allyn; Šmajs, David

Crystallization of FcpA from Leptospira, a novel flagellar protein that is essential for pathogenesis

钩端螺旋体FcpA的结晶,FcpA是一种新型鞭毛蛋白,对致病性至关重要。

San Martin, Fabiana; Mechaly, Ariel E; Larrieux, Nicole; Wunder, Elsio A Jr; Ko, Albert I; Picardeau, Mathieu; Trajtenberg, Felipe; Buschiazzo, Alejandro

Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action

通过激酶-调节复合物作用的三维快照揭示信号传导方向性的调控

Trajtenberg, Felipe; Imelio, Juan A; Machado, Matías R; Larrieux, Nicole; Marti, Marcelo A; Obal, Gonzalo; Mechaly, Ariel E; Buschiazzo, Alejandro

Segmental helical motions and dynamical asymmetry modulate histidine kinase autophosphorylation

节段螺旋运动和动态不对称性调节组氨酸激酶的自身磷酸化

Mechaly, Ariel E; Sassoon, Nathalie; Betton, Jean-Michel; Alzari, Pedro M