日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Host Aging Induces a Senescent-Like Phenotype in Neutrophils and Altered Transcriptional Responses to Streptococcus pneumoniae

宿主衰老诱导中性粒细胞出现衰老样表型并改变对肺炎链球菌的转录反应

Battaglia, Michael C; Bhalla, Manmeet; Marzullo, Brandon; Betadpur, Anagha; Lenhard, Alexsandra P; Mohamed, Rania Hassan; Kalem, Murat C; Heinzinger, Lauren R; Leus, Pathricia A; Labarron, Samuel; Garrett-Sinha, Lee Ann; Mecsas, Joan; Blumental-Perry, Anna; Bou Ghanem, Elsa N

Large-scale combination screens reveal small-molecule sensitization of antibiotic-resistant gram-negative ESKAPE pathogens

大规模联合筛选揭示小分子药物对耐药革兰氏阴性ESKAPE病原体的增敏作用

Tse, Megan W; Zhu, Meilin; Peters, Benjamin; Hamami, Efrat; Chen, Julie; Davis, Kathleen P; Nitz, Samuel; Weller, Juliane; Warrier, Thulasi; Hunt, Diana K; Morales, Yoelkys; Kawate, Tomohiko; Gaulin, Jeffrey L; Come, Jon H; Hernandez-Bird, Juan; Huo, Wenwen; Neisewander, Isabelle; Yu, Xiao; Aceves-Salvador, Jose A; Kiessling, Laura L; Hung, Deborah T; Mecsas, Joan; Aldridge, Bree B; Isberg, Ralph R; Blainey, Paul C

A Multicenter Study to Assess Avoidant/Restrictive Food Intake Disorder in Patients with Inflammatory Bowel Disease

一项评估炎症性肠病患者回避/限制性食物摄入障碍的多中心研究

Grossberg, Laurie B; Mishra, Kajali; Rabinowitz, Loren G; Mecsas-Faxon, Benjamin; Mandal, Nivedita; Susheela, Ammu; Naik, Amar; Patel, Krishna; Gallotto, Marissa; Greenwood, Tara; Burton Murray, Helen; Papamichael, Konstantinos; Cheifetz, Adam S; Kinsinger, Sarah W; Ballou, Sarah

Host aging induces a senescent-like phenotype in neutrophils and altered transcriptional responses to Streptococcus pneumoniae

宿主衰老会诱导中性粒细胞出现衰老样表型,并改变其对肺炎链球菌的转录反应。

Battaglia, Michael C; Bhalla, Manmeet; Marzullo, Brandon; Betadpur, Anagha; Lenhard, Alexsandra P; Mohamed, Rania Hassan; Kalem, Murat C; Heinzinger, Lauren R; Leus, Pathricia A; Garrett-Sinha, Lee Ann; Mecsas, Joan; Blumental-Perry, Anna; Ghanem, Elsa N Bou

Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection

RIPK1 的非典型自身磷酸化可及时驱动细胞焦亡以控制耶尔森氏菌感染

David Jetton, Hayley I Muendlein, Wilson M Connolly, Zoie Magri, Irina Smirnova, Rebecca Batorsky, Joan Mecsas, Alexei Degterev, Alexander Poltorak

Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses

培养基在检测模拟体内反应的革兰氏阴性菌药物相互作用中起着至关重要的作用

Davis, Kathleen P; Morales, Yoelkys; Ende, Rachel J; Peters, Ryan; McCabe, Anne L; Mecsas, Joan; Aldridge, Bree B

Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers

假结核耶尔森菌YopE可阻止M细胞摄取,并诱导人回肠类器官来源的单层细胞中M细胞的排出。

Fasciano, Alyssa C; Dasanayake, Gaya S; Estes, Mary K; Zachos, Nicholas C; Breault, David T; Isberg, Ralph R; Tan, Shumin; Mecsas, Joan

Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

中性粒细胞在受到C型凝集素和念珠菌刺激后,需要SKAP2才能产生活性氧。

Giang T Nguyen ,Shuying Xu ,Walter Adams ,John M Leong ,Stephen C Bunnell ,Michael K Mansour ,David B Sykes ,Joan Mecsas

Role of the Yersinia pseudotuberculosis Virulence Plasmid in Pathogen-Phagocyte Interactions in Mesenteric Lymph Nodes

假结核耶尔森菌毒力质粒在肠系膜淋巴结病原体-吞噬细胞相互作用中的作用

Bliska, James B; Brodsky, Igor E; Mecsas, Joan

SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst

SKAP2是抵御肺炎克雷伯菌感染和中性粒细胞呼吸爆发所必需的

Giang T Nguyen ,Lamyaa Shaban ,Matthias Mack ,Kenneth D Swanson ,Stephen C Bunnell ,David B Sykes ,Joan Mecsas