日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration

每周口服给药的 DRD2 拮抗剂 ONC201 在晚期实体瘤患者中的安全性和增强的免疫刺激活性

Stein, Mark N; Malhotra, Jyoti; Tarapore, Rohinton S; Malhotra, Usha; Silk, Ann W; Chan, Nancy; Rodriguez, Lorna; Aisner, Joseph; Aiken, Robert D; Mayer, Tina; Haffty, Bruce G; Newman, Jenna H; Aspromonte, Salvatore M; Bommareddy, Praveen K; Estupinian, Ricardo; Chesson, Charles B; Sadimin, Evita T; Li, Shengguo; Medina, Daniel J; Saunders, Tracie; Frankel, Melissa; Kareddula, Aparna; Damare, Sherrie; Wesolowsky, Elayne; Gabel, Christian; El-Deiry, Wafik S; Prabhu, Varun V; Allen, Joshua E; Stogniew, Martin; Oster, Wolfgang; Bertino, Joseph R; Libutti, Steven K; Mehnert, Janice M; Zloza, Andrew

BMI-1 Targeting Interferes with Patient-Derived Tumor-Initiating Cell Survival and Tumor Growth in Prostate Cancer.

BMI-1靶向治疗干扰前列腺癌患者来源的肿瘤起始细胞的存活和肿瘤生长

Bansal Nitu, Bartucci Monica, Yusuff Shamila, Davis Stephani, Flaherty Kathleen, Huselid Eric, Patrizii Michele, Jones Daniel, Cao Liangxian, Sydorenko Nadiya, Moon Young-Choon, Zhong Hua, Medina Daniel J, Kerrigan John, Stein Mark N, Kim Isaac Y, Davis Thomas W, DiPaola Robert S, Bertino Joseph R, Sabaawy Hatem E

Fulvestrant treatment alters MDM2 protein turnover and sensitivity of human breast carcinoma cells to chemotherapeutic drugs

氟维司群治疗会改变MDM2蛋白的周转率以及人乳腺癌细胞对化疗药物的敏感性

Dolfi, Sonia C; Jäger, Adriana V; Medina, Daniel J; Haffty, Bruce G; Yang, Jin-Ming; Hirshfield, Kim M

Mesenchymal stromal cells protect mantle cell lymphoma cells from spontaneous and drug-induced apoptosis through secretion of B-cell activating factor and activation of the canonical and non-canonical nuclear factor κB pathways

间充质基质细胞通过分泌B细胞激活因子和激活经典和非经典核因子κB通路,保护套细胞淋巴瘤细胞免受自发性和药物诱导的细胞凋亡。

Medina, Daniel J; Goodell, Lauri; Glod, John; Gélinas, Céline; Rabson, Arnold B; Strair, Roger K

Plitidepsin (Aplidin) is a potent inhibitor of diffuse large cell and Burkitt lymphoma and is synergistic with rituximab

普利替地辛(Aplidin)是弥漫性大B细胞淋巴瘤和伯基特淋巴瘤的强效抑制剂,并与利妥昔单抗具有协同作用。

Barboza, Nora M; Medina, Daniel J; Budak-Alpdogan, Tulin; Aracil, Miguel; Jimeno, José M; Bertino, Joseph R; Banerjee, Debabrata