Meehyein相关文献与解析，生知库 | 链接生命科学的每一步

Jun12682, a potent SARS-CoV-2 papain-like protease inhibitor with exceptional antiviral efficacy in mice

Jun12682 是一种强效的 SARS-CoV-2 木瓜蛋白酶样蛋白酶抑制剂，在小鼠中具有卓越的抗病毒功效。

期刊:Acta Pharmaceutica Sinica B

影响因子:14.6

doi:10.1016/j.apsb.2024.07.001

Yang, Mianling; Kim, Meehyein; Zhan, Peng

A dual inhibitor of PIP5K1C and PIKfyve prevents SARS-CoV-2 entry into cells

PIP5K1C 和 PIKfyve 的双重抑制剂可阻止 SARS-CoV-2 进入细胞

期刊:Experimental and Molecular Medicine

影响因子:9.5

doi:10.1038/s12276-024-01283-2

Yuri Seo #, Yejin Jang #, Seon-Gyeong Lee #, Joon Ho Rhlee, Sukyeong Kong, Thi Tuyet Hanh Vo, Myung Hun Kim, Myoung Kyu Lee, Byungil Kim, Sung You Hong, Meehyein Kim, Joo-Yong Lee, Kyungjae Myung2

Miniaturized Modular Click Chemistry-enabled Rapid Discovery of Unique SARS-CoV-2 Mpro Inhibitors With Robust Potency and Drug-like Profile

利用微型模块化点击化学快速发现具有强大药效和类药物特性的独特 SARS-CoV-2 Mpro 抑制剂

期刊:Advanced Science

影响因子:

doi:10.1002/advs.202404884

Mianling Yang, Myoung Kyu Lee, Shenghua Gao, Letian Song, Hye-Yeon Jang, Inseong Jo, Chun-Chiao Yang, Katharina Sylvester, Chunkyu Ko, Shuo Wang, Bing Ye, Kai Tang, Junyi Li, Manyu Gu, Christa E Müller, Norbert Sträter, Xinyong Liu, Meehyein Kim, Peng Zhan

Label-free detection and discrimination of respiratory pathogens based on electrochemical synthesis of biomaterials-mediated plasmonic composites and machine learning analysis

基于生物材料介导等离子体复合材料电化学合成和机器学习分析的呼吸道病原体无标记检测与鉴别

期刊:Biosensors & Bioelectronics

影响因子:10.5

doi:10.1016/j.bios.2023.115178

Ansah, Iris Baffour; Leming, Matthew; Lee, Soo Hyun; Yang, Jun-Yeong; Mun, ChaeWon; Noh, Kyungseob; An, Timothy; Lee, Seunghun; Kim, Dong-Ho; Kim, Meehyein; Im, Hyungsoon; Park, Sung-Gyu

微生物学

发表日期：2023

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Evaluation of Antiviral Activity of Gemcitabine Derivatives against Influenza Virus and Severe Acute Respiratory Syndrome Coronavirus 2

吉西他滨衍生物对流感病毒和严重急性呼吸综合征冠状病毒2的抗病毒活性评价

期刊:ACS Infectious Diseases

影响因子:4

doi:10.1021/acsinfecdis.3c00034

Hyeon-Min Cha, Uk-Il Kim, Soo Bin Ahn, Myoung Kyu Lee, Haemi Lee, Hyungtae Bang, Yejin Jang, Seong Soon Kim, Myung Ae Bae, Kyungjin Kim, Meehyein Kim

Synthesis and biological evaluation of new β-D-N(4)-hydroxycytidine analogs against SARS-CoV-2, influenza viruses and DENV-2

合成并生物学评价新型β-DN(4)-羟基胞苷类似物对抗SARS-CoV-2、流感病毒和DENV-2的活性

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2023.129174

An, Yeon Jin; Choi, Se Myeong; Choi, Eun Rang; Nam, Ye Eun; Seo, Eun Woo; Ahn, Soo Bin; Jang, Yejin; Kim, Meehyein; Cho, Jong Hyun

Generation of human tonsil epithelial organoids as an ex vivo model for SARS-CoV-2 infection

构建人扁桃体上皮类器官作为SARS-CoV-2感染的体外模型

期刊:Biomaterials

影响因子:12.8

doi:10.1016/j.biomaterials.2022.121460

Han Kyung Kim ，Hyeryeon Kim ，Myoung Kyu Lee ，Woo Hee Choi ，Yejin Jang ，Jin Soo Shin ，Jun-Yeol Park ，Dong Hyuck Bae ，Seong-In Hyun ，Kang Hyun Kim ，Hyun Wook Han ，Byungho Lim ，Gildon Choi ，Meehyein Kim ，Young Chang Lim ，Jongman Yoo

The efficacy of a 2,4-diaminoquinazoline compound as an intranasal vaccine adjuvant to protect against influenza A virus infection in vivo

2,4-二氨基喹唑啉化合物作为鼻内疫苗佐剂在体内预防甲型流感病毒感染的有效性

期刊:Journal of Microbiology

影响因子:2.6

doi:10.1007/s12275-022-1661-7

Noh, Kyungseob; Jeong, Eun Ju; An, Timothy; Shin, Jin Soo; Kim, Hyejin; Han, Soo Bong; Kim, Meehyein

Antiviral activity of lambda-carrageenan against influenza viruses and severe acute respiratory syndrome coronavirus 2

λ-角叉菜胶对流感病毒和严重急性呼吸综合征冠状病毒 2 的抗病毒活性

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-020-80896-9

Yejin Jang, Heegwon Shin, Myoung Kyu Lee, Oh Seung Kwon, Jin Soo Shin, Yong-Il Kim, Chan Woo Kim, Hye-Ra Lee, Meehyein Kim

Antiviral drug discovery and development: challenges and future directions

抗病毒药物的发现与开发：挑战与未来方向

Jun12682, a potent SARS-CoV-2 papain-like protease inhibitor with exceptional antiviral efficacy in mice

Jun12682 是一种强效的 SARS-CoV-2 木瓜蛋白酶样蛋白酶抑制剂，在小鼠中具有卓越的抗病毒功效。

A dual inhibitor of PIP5K1C and PIKfyve prevents SARS-CoV-2 entry into cells

PIP5K1C 和 PIKfyve 的双重抑制剂可阻止 SARS-CoV-2 进入细胞

Miniaturized Modular Click Chemistry-enabled Rapid Discovery of Unique SARS-CoV-2 Mpro Inhibitors With Robust Potency and Drug-like Profile

利用微型模块化点击化学快速发现具有强大药效和类药物特性的独特 SARS-CoV-2 Mpro 抑制剂

Label-free detection and discrimination of respiratory pathogens based on electrochemical synthesis of biomaterials-mediated plasmonic composites and machine learning analysis

基于生物材料介导等离子体复合材料电化学合成和机器学习分析的呼吸道病原体无标记检测与鉴别

Evaluation of Antiviral Activity of Gemcitabine Derivatives against Influenza Virus and Severe Acute Respiratory Syndrome Coronavirus 2

吉西他滨衍生物对流感病毒和严重急性呼吸综合征冠状病毒2的抗病毒活性评价

Synthesis and biological evaluation of new β-D-N(4)-hydroxycytidine analogs against SARS-CoV-2, influenza viruses and DENV-2

合成并生物学评价新型β-DN(4)-羟基胞苷类似物对抗SARS-CoV-2、流感病毒和DENV-2的活性

Generation of human tonsil epithelial organoids as an ex vivo model for SARS-CoV-2 infection

构建人扁桃体上皮类器官作为SARS-CoV-2感染的体外模型

The efficacy of a 2,4-diaminoquinazoline compound as an intranasal vaccine adjuvant to protect against influenza A virus infection in vivo

2,4-二氨基喹唑啉化合物作为鼻内疫苗佐剂在体内预防甲型流感病毒感染的有效性

Antiviral activity of lambda-carrageenan against influenza viruses and severe acute respiratory syndrome coronavirus 2

λ-角叉菜胶对流感病毒和严重急性呼吸综合征冠状病毒 2 的抗病毒活性