日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Dual Inhibitors of SARS-CoV-2 3CL Protease and Human Cathepsin L Containing Glutamine Isosteres Are Anti-CoV-2 Agents.

含有谷氨酰胺同分异构体的SARS-CoV-2 3CL蛋白酶和人组织蛋白酶L双重抑制剂是抗CoV-2药物

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c11620
Kumar Vivek, Zhu Jiyun, Chenna Bala C, Hoffpauir Zoe A, Rademacher Andrew, Rogers Ashley M, Tseng Chien-Te, Drelich Aleksandra, Farzandh Sharfa, Lamb Audrey L, Meek Thomas D
炎症/感染
新冠
Human
药物研究
发表日期：2025
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Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics

通过稳态和预稳态动力学确定SARS-CoV-2 3-胰凝乳蛋白酶样蛋白酶的催化机制

期刊:ACS Catalysis
影响因子:13.1
doi:10.1021/acscatal.4c04695
Zhu, Jiyun; Kemp, Alexandria M; Chenna, Bala C; Kumar, Vivek; Rademacher, Andrew; Yun, Sangho; Laganowsky, Arthur; Meek, Thomas D
SARS-CoV-2
发表日期：2024
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Insights into the Main Protease of SARS-CoV-2: Thermodynamic Analysis, Structural Characterization, and the Impact of Inhibitors

对SARS-CoV-2主蛋白酶的深入研究：热力学分析、结构表征及抑制剂的影响

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.4c02311
Butalewicz, Jamie P; Sipe, Sarah N; Juetten, Kyle J; James, Virginia K; Kim, Kangsan; Zhang, Y Jessie; Meek, Thomas D; Brodbelt, Jennifer S
SARS-CoV-2
发表日期：2024
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Self-Masked Aldehyde Inhibitors of Human Cathepsin L Are Potent Anti-CoV-2 Agents

人类组织蛋白酶L的自掩蔽醛类抑制剂是强效抗CoV-2药物

期刊:Frontiers in Chemistry
影响因子:4.2
doi:10.3389/fchem.2022.867928
Zhu, Jiyun; Li, Linfeng; Drelich, Aleksandra; Chenna, Bala C; Mellott, Drake M; Taylor, Zane W; Tat, Vivian; Garcia, Christopher Z; Katzfuss, Ardala; Tseng, Chien-Te K; Meek, Thomas D
Human
发表日期：2022
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