日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conditional activation of Cas13 enforces lysogeny in a native type VI-A CRISPR host

Cas13 的条件性激活可使天然 VI-A 型 CRISPR 宿主细胞发生溶原性转变

Godsil, Marshall; Wei, Nova; Meeske, Alexander J

Design of highly functional genome editors by modelling CRISPR-Cas sequences

通过对 CRISPR-Cas 序列进行建模来设计高功能基因组编辑器

Ruffolo, Jeffrey A; Nayfach, Stephen; Gallagher, Joseph; Bhatnagar, Aadyot; Beazer, Joel; Hussain, Riffat; Russ, Jordan; Yip, Jennifer; Hill, Emily; Pacesa, Martin; Meeske, Alexander J; Cameron, Peter; Madani, Ali

RNA-mediated CRISPR-Cas13 inhibition through crRNA structural mimicry

通过crRNA结构模拟实现RNA介导的CRISPR-Cas13抑制

Hayes, Victoria M; Zhang, Jun-Tao; Katz, Mark A; Li, Yuelong; Kocsis, Benjamin; Brinkley, David M; Jia, Ning; Meeske, Alexander J

Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri.

三种 CRISPR-Cas 类型之间的串扰使得李斯特菌能够启动 VI-A 型适应

Margolis Shally R, Meeske Alexander J

Gut phages and their interactions with bacterial and mammalian hosts

肠道噬菌体及其与细菌和哺乳动物宿主的相互作用

Godsil, Marshall; Ritz, Nathaniel L; Venkatesh, Siddarth; Meeske, Alexander J

Engineering of CRISPR-Cas PAM recognition using deep learning of vast evolutionary data

利用深度学习对海量进化数据进行CRISPR-Cas PAM识别的工程改造

Nayfach, Stephen; Bhatnagar, Aadyot; Novichkov, Andrey; Estevam, Gabriella O; Kim, Nahye; Hill, Emily; Ruffolo, Jeffrey A; Silverstein, Rachel; Gallagher, Joseph; Kleinstiver, Benjamin; Meeske, Alexander J; Cameron, Peter; Madani, Ali

Diverse viral cas genes antagonize CRISPR immunity

多种病毒cas基因拮抗CRISPR免疫

Katz, Mark A; Sawyer, Edith M; Oriolt, Luke; Kozlova, Albina; Williams, Madison C; Margolis, Shally R; Johnson, Matthew; Bondy-Denomy, Joseph; Meeske, Alexander J

Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri

三种 CRISPR-Cas 类型之间的相互作用使李斯特菌(Listeria seeligeri)能够启动 VI-A 型适应。

Margolis, Shally R; Meeske, Alexander J

Lack of Cas13a inhibition by anti-CRISPR proteins from Leptotrichia prophages

来自纤毛虫原噬菌体的抗CRISPR蛋白对Cas13a缺乏抑制作用

Johnson, Matthew C; Hille, Logan T; Kleinstiver, Benjamin P; Meeske, Alexander J; Bondy-Denomy, Joseph

A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity

噬菌体编码的抗CRISPR抗体能够完全逃避VI-A型CRISPR-Cas免疫反应。

Meeske, Alexander J; Jia, Ning; Cassel, Alice K; Kozlova, Albina; Liao, Jingqiu; Wiedmann, Martin; Patel, Dinshaw J; Marraffini, Luciano A