Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis

利用靶向内皮唾液酸蛋白（CD248）的CAR-T细胞攻击活化的微环境，可清除血管周围细胞，从而抑制肿瘤生长和转移。