日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Methotrexate inhibits BMP4 and abrogates the hypertrophic chondrocyte phenotype of synovial fibroblasts in juvenile idiopathic arthritis

甲氨蝶呤抑制 BMP4 并消除幼年特发性关节炎滑膜成纤维细胞的肥大性软骨细胞表型

Megan M Simonds, Samuel T Freer, Anne Marie C Brescia

The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes

幼年特发性关节炎滑膜成纤维细胞的培养微环境有利于通过 BMP4 进行软骨内骨形成,并受到软骨细胞的抑制

Megan M Simonds, Amanda R Schlefman, Suzanne M McCahan, Kathleen E Sullivan, Carlos D Rose, Anne Marie C Brescia

Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation

幼年特发性关节炎成纤维细胞样滑膜细胞影响软骨细胞,从而改变 BMP 拮抗剂的表达,表明参与软骨内骨形成的两种主要细胞类型之间存在相互作用

Megan M Simonds, Amanda R Schlefman, Suzanne M McCahan, Kathleen E Sullivan, Carlos D Rose, AnneMarie C Brescia

Prior to extension, Transcriptomes of fibroblast-like Synoviocytes from extended and Polyarticular juvenile idiopathic arthritis are indistinguishable

在扩展之前,来自扩展和多关节型幼年特发性关节炎的成纤维细胞样滑膜细胞的转录组难以区分

AnneMarie C Brescia, Megan M Simonds, Suzanne M McCahan, Kathleen E Sullivan, Carlos D Rose

Secretion of pro-inflammatory cytokines and chemokines and loss of regulatory signals by fibroblast-like synoviocytes in juvenile idiopathic arthritis

幼年特发性关节炎中成纤维细胞样滑膜细胞分泌促炎细胞因子和趋化因子以及失去调节信号

AnneMarie C Brescia, Megan M Simonds, Kathleen E Sullivan, Carlos D Rose