日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Artificial intelligence challenges in the face of biological threats: emerging catastrophic risks for public health

人工智能在生物威胁面前面临的挑战:公共卫生领域正在涌现的灾难性风险

de Lima, Renan Chaves; Sinclair, Lucas; Megger, Ricardo; Maciel, Magno Alessandro Guedes; Vasconcelos, Pedro Fernando da Costa; Quaresma, Juarez Antônio Simões

Identification of risk factors for post-intensive care syndrome in family members (PICS-F) among adult patients: a systematic review

成人患者重症监护后综合征(PICS-F)家庭成员危险因素的识别:系统评价

Putowski, Zbigniew; Rachfalska, Natalia; Majewska, Karolina; Megger, Katarzyna; Krzych, Łukasz

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology

在急性病毒感染期间,采用抗PD-L1抗体联合免疫疗法并清除调节性T细胞,可改善病毒控制,但会导致致命的免疫病理。

David, Paul; Drabczyk-Pluta, Malgorzata; Pastille, Eva; Knuschke, Torben; Werner, Tanja; Honke, Nadine; Megger, Dominik A; Akhmetzyanova, Ilseyar; Shaabani, Namir; Eyking-Singer, Annette; Cario, Elke; Kershaw, Olivia; Gruber, Achim D; Tenbusch, Matthias; Dietze, Kirsten K; Trilling, Mirko; Liu, Jia; Schadendorf, Dirk; Streeck, Hendrik; Lang, Karl S; Xie, Youhua; Zimmer, Lisa; Sitek, Barbara; Paschen, Annette; Westendorf, Astrid M; Dittmer, Ulf; Zelinskyy, Gennadiy

The PD-1/PD-L1 Pathway Affects the Expansion and Function of Cytotoxic CD8(+) T Cells During an Acute Retroviral Infection

PD-1/PD-L1通路影响急性逆转录病毒感染期间细胞毒性CD8(+) T细胞的扩增和功能

David, Paul; Megger, Dominik A; Kaiser, Tamara; Werner, Tanja; Liu, Jia; Chen, Lieping; Sitek, Barbara; Dittmer, Ulf; Zelinskyy, Gennadiy

Label-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-α Identifies Antiviral Proteins Enriched in Exosomes

对用 IFN-α 处理的 THP-1 衍生巨噬细胞分泌的外泌体进行无标记蛋白质组学分析,鉴定出外泌体中富含的抗病毒蛋白

Zhenlan Yao, Xiaofang Jia, Dominik A Megger, Jieliang Chen, Yuyi Liu, Jianhua Li, Barbara Sitek, Zhenghong Yuan

Correction to: Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

更正:肝癌细胞系明显模拟了相应人类肿瘤的代谢基因表达模式

Nwosu, Zeribe C; Battello, Nadia; Rothley, Melanie; Piorońska, Weronika; Sitek, Barbara; Ebert, Matthias P; Hofmann, Ute; Sleeman, Jonathan; Wölfl, Stefan; Meyer, Christoph; Megger, Dominik A; Dooley, Steven

Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

肝癌细胞系明显模仿相应人类肿瘤的代谢基因表达模式

Zeribe C Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A Megger, Steven Dooley1

A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx

基于质谱的病毒 DDB1 和 Cullin 泛素连接酶结合蛋白相互作用组分析揭示了 HIV-2 编码的 Vpx 的 NF-κB 抑制活性

Christine D Landsberg, Dominik A Megger, Dominik Hotter, Meike U Rückborn, Mareike Eilbrecht, Jassin Rashidi-Alavijeh, Sebastian Howe, Stefan Heinrichs, Daniel Sauter, Barbara Sitek, Vu Thuy Khanh Le-Trilling, Mirko Trilling

Mixed guanine, adenine base quartets: possible roles of protons and metal ions in their stabilization

混合鸟嘌呤、腺嘌呤碱基四联体:质子和金属离子在其稳定中的可能作用

Megger, Dominik A; Lax, Patrick M; Paauwe, Jeroen; Fonseca Guerra, Célia; Lippert, Bernhard

A metal-mediated base pair that discriminates between the canonical pyrimidine nucleobases

一种金属介导的碱基对,能够区分典型的嘧啶核碱基。

Jash, Biswarup; Scharf, Philipp; Sandmann, Nikolas; Fonseca Guerra, Célia; Megger, Dominik A; Müller, Jens