日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Blood biomarkers and breed genetics of aging in pet dogs

宠物犬衰老的血液生物标志物和品种遗传学

Sohrab, Vista; White, Michelle E; Harrison, Benjamin R; Bierman, Rob; Marye, Abbey; Pirovich, Kathleen Morrill; Genereux, Diane P; Megquier, Kate; Li, Xue; Kenney, Brittney; Reichel, Cindy; Snyder-Mackler, Noah; Akey, Joshua M; Promislow, Daniel E L; Chen, Frances L; Karlsson, Elinor K

Characterization of the genomic landscape of canine oral osteosarcoma reveals similarities with appendicular osteosarcoma

犬口腔骨肉瘤基因组图谱的特征分析揭示了其与四肢骨肉瘤的相似之处

Husted, Christopher; Adrianowycz, Sarah; Peterson, Cornelia; DeWitt, Suzanne Bartholf; Karlsson, Elinor K; Eward, William; Somarelli, Jason A; Megquier, Kate; Gardner, Heather L

Impact of preanalytical factors on liquid biopsy in the canine cancer model

分析前因素对犬癌症模型液体活检的影响

Megquier, Kate; Husted, Christopher; Rhoades, Justin; White, Michelle E; Genereux, Diane P; Chen, Frances L; Xiong, Kan; Kwon, Euijin; Swofford, Ross; Painter, Corrie; Adalsteinsson, Viktor; London, Cheryl A; Gardner, Heather L; Karlsson, Elinor K

Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics

致癌基因中共同的热点突变使狗成为精准治疗无与伦比的比较模型

Lucas Rodrigues, Joshua Watson, Yuan Feng, Benjamin Lewis, Garrett Harvey, Gerald Post, Kate Megquier, Michelle E White, Lindsay Lambert, Aubrey Miller, Christina Lopes, Shaying Zhao

Ancestry-inclusive dog genomics challenges popular breed stereotypes

包含祖先信息的犬类基因组学挑战了人们对犬种的刻板印象

Morrill, Kathleen; Hekman, Jessica; Li, Xue; McClure, Jesse; Logan, Brittney; Goodman, Linda; Gao, Mingshi; Dong, Yinan; Alonso, Marjie; Carmichael, Elena; Snyder-Mackler, Noah; Alonso, Jacob; Noh, Hyun Ji; Johnson, Jeremy; Koltookian, Michele; Lieu, Charlie; Megquier, Kate; Swofford, Ross; Turner-Maier, Jason; White, Michelle E; Weng, Zhiping; Colubri, Andrés; Genereux, Diane P; Lord, Kathryn A; Karlsson, Elinor K

The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations

犬骨肉瘤细胞系的基因组图谱揭示了保守的结构复杂性和通路改变

Megquier, Kate; Turner-Maier, Jason; Morrill, Kathleen; Li, Xue; Johnson, Jeremy; Karlsson, Elinor K; London, Cheryl A; Gardner, Heather L

Lifetime prevalence of malignant and benign tumours in companion dogs: Cross-sectional analysis of Dog Aging Project baseline survey

伴侣犬恶性肿瘤和良性肿瘤的终生患病率:犬类衰老项目基线调查的横断面分析

Schwartz, Stephen M; Urfer, Silvan R; White, Michelle; Megquier, Kate; Shrager, Sandi; Ruple, Audrey

Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions

基因组复杂的人类血管肉瘤和犬血管肉瘤建立了由新型基因融合驱动的趋同血管生成转录程序

Kim, Jong Hyuk; Megquier, Kate; Thomas, Rachael; Sarver, Aaron L; Song, Jung Min; Kim, Yoon Tae; Cheng, Nuojin; Schulte, Ashley J; Linden, Michael A; Murugan, Paari; Oseth, LeAnn; Forster, Colleen L; Elvers, Ingegerd; Swofford, Ross; Turner-Maier, Jason; Karlsson, Elinor K; Breen, Matthew; Lindblad-Toh, Kerstin; Modiano, Jaime F

Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the CDKN2A/B Gene Locus as a Major Risk Locus

莱昂贝格犬骨肉瘤全基因组分析表明 CDKN2A/B 基因位点是主要风险位点

Anna Letko, Katie M Minor, Elaine M Norton, Voichita D Marinescu, Michaela Drögemüller, Emma Ivansson, Kate Megquier, Hyun Ji Noh, Mike Starkey, Steven G Friedenberg, Kerstin Lindblad-Toh, James R Mickelson, Cord Drögemüller

Improving Cancer Drug Discovery by Studying Cancer across the Tree of Life

通过研究生命之树上的癌症来改进癌症药物研发

Somarelli, Jason A; Boddy, Amy M; Gardner, Heather L; DeWitt, Suzanne Bartholf; Tuohy, Joanne; Megquier, Kate; Sheth, Maya U; Hsu, Shiaowen David; Thorne, Jeffrey L; London, Cheryl A; Eward, William C