日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Prevention of tuberculosis in cynomolgus macaques by an attenuated Mycobacterium tuberculosis vaccine candidate

利用减毒结核分枝杆菌候选疫苗预防食蟹猴结核病

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-57090-4
Singh, Dhiraj K; Ahmed, Mushtaq; Akter, Sadia; Shivanna, Vinay; Bucşan, Allison N; Mishra, Abhishek; Golden, Nadia A; Didier, Peter J; Doyle, Lara A; Hall-Ursone, Shannan; Roy, Chad J; Arora, Garima; Dick, Edward J Jr; Jagannath, Chinnaswamy; Mehra, Smriti; Khader, Shabaana A; Kaushal, Deepak
发表日期：2025
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Development and preclinical evaluation of next-generation ΔsigH-based live candidate vaccines

基于ΔsigH的下一代活疫苗的研发和临床前评估

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.195947
Arora, Garima; Munson, Caden W; Ahmed, Mushtaq; Shivanna, Vinay; Devi, Annu; Devireddy, Venkata Sr; Antony, Basil; Hall-Ursone, Shannan; Gonzalez, Olga D; Dick, Edward J Jr; Jagannath, Chinnaswamy; Alvarez, Xavier; Mehra, Smriti; Khader, Shabaana A; Singh, Dhiraj K; Kaushal, Deepak
发表日期：2025
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Distinct clinical outcomes in pediatric tuberculosis: A study utilizing infant macaques exposed to aerosol Mycobacterium tuberculosis

儿童结核病临床结局的差异：一项利用暴露于气溶胶结核分枝杆菌的幼年猕猴进行的研究

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.112899
Turnbull, Katherine; Vincent, Eunice; Xu, Huanbin; Didier, Peter J; Blair, Robert V; Doyle-Meyers, Lara A; Roy, Chad J; Mehra, Smriti; Kaushal, Deepak; Veazey, Ronald S; Wang, Xiaolei
发表日期：2025
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Increased vaccine efficacy against tuberculosis with a recombinant BCG overexpressing the STING agonist cyclic di-AMP

重组卡介苗过表达STING激动剂环二腺苷酸环化酶抑制剂（c-di-AMP）可提高抗结核病疫苗的效力。

期刊:
影响因子:
doi:10.1101/2025.07.17.665241
Singh, Dhiraj K; Um, Peter; Arora, Garima; Alvarez, Xavier; Shivanna, Vinay; Dick, Edward Jr; Mehra, Smriti; Bishai, William R
STING
发表日期：2025
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Therapeutic remodeling of the tuberculosis granuloma with 1-methyl-D-tryptophan enhances CD8(+) T cell-macrophage interactions

利用1-甲基-D-色氨酸对结核肉芽肿进行治疗性重塑可增强CD8(+) T细胞与巨噬细胞的相互作用。

期刊:
影响因子:
doi:10.1101/2025.10.02.680083
McCaffrey, Erin F; Delmastro, Alea C; Singh, Bindu; Devi, Annu; Golden, Nadia A; Khader, Shabaana A; Angelo, Michael; Kaushal, Deepak; Mehra, Smriti
巨噬细胞
T细胞
炎症/感染
巨噬细胞
CD8
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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Using Imaris to rigorously track PET-defined sites of lung inflammation in Mycobacterium tuberculosis-exposed non-human primates

利用 Imaris 技术严格追踪暴露于结核分枝杆菌的非人灵长类动物肺部炎症的 PET 定义部位

期刊:
影响因子:
doi:10.1101/2025.07.04.663191
Hurtado, Estefania; Alvarez, Xavier; Kaushal, Deepak; Mehra, Smriti; Ganusov, Vitaly V
肺炎
炎症/感染
炎症
发表日期：2025
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Concurrent TB and HIV therapies control TB reactivation during co-infection but not chronic immune activation

同时进行结核病和艾滋病治疗可以控制合并感染期间的结核病复发，但不能控制慢性免疫激活。

期刊:Nature Communications
影响因子:
doi:10.1038/s41467-025-67188-4
Sharan, Riti; Zou, Yi; Singh, Bindu; Shivanna, Vinay; Dick, Edward J Jr; Hall-Ursone, Shannan; Luo, Xi; Guo, Guanlin; Khader, Shabaana A; Alvarez, Xavier; Rengarajan, Jyothi; Lai, Zhao; Mehra, Smriti; Wu, Hulin; Kaushal, Deepak
炎症/感染
免疫/内分泌
发表日期：2025
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Indoleamine-2,3-dioxygenase inhibition improves immunity and is safe for concurrent use with cART during Mtb/SIV coinfection

吲哚胺-2,3-双加氧酶抑制剂可增强免疫力，并且在结核分枝杆菌/SIV合并感染期间与cART同时使用是安全的。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.179317
Singh, Bindu; Sharan, Riti; Ravichandran, Gayathri; Escobedo, Ruby; Shivanna, Vinay; Dick, Edward J Jr; Hall-Ursone, Shannan; Arora, Garima; Alvarez, Xavier; Singh, Dhiraj K; Kaushal, Deepak; Mehra, Smriti
炎症/感染
免疫/内分泌
发表日期：2024
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Concurrent TB and HIV therapies effectively control clinical reactivation of TB during co-infection but fail to eliminate chronic immune activation

同时进行结核病和艾滋病治疗可以有效控制合并感染期间结核病的临床复发，但无法消除慢性免疫激活。

期刊:
影响因子:
doi:10.21203/rs.3.rs-4908400/v1
Sharan, Riti; Zou, Yi; Lai, Zhao; Singh, Bindu; Shivanna, Vinay; Dick, Edward Jr; Hall-Ursone, Shannan; Khader, Shabaana; Mehra, Smriti; Alvarez, Xavier; Rengarajan, Jyothi; Kaushal, Deepak
炎症/感染
免疫/内分泌
发表日期：2024
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Author Correction: The immunoregulatory landscape of human tuberculosis granulomas

作者更正：人类结核肉芽肿的免疫调节图谱

期刊:Nature Immunology
影响因子:27.6
doi:10.1038/s41590-022-01178-2
McCaffrey, Erin F; Donato, Michele; Keren, Leeat; Chen, Zhenghao; Delmastro, Alea; Fitzpatrick, Megan B; Gupta, Sanjana; Greenwald, Noah F; Baranski, Alex; Graf, William; Kumar, Rashmi; Bosse, Marc; Fullaway, Christine Camacho; Ramdial, Pratista K; Forgó, Erna; Jojic, Vladimir; Van Valen, David; Mehra, Smriti; Khader, Shabaana A; Bendall, Sean C; van de Rijn, Matt; Kalman, Daniel; Kaushal, Deepak; Hunter, Robert L; Banaei, Niaz; Steyn, Adrie J C; Khatri, Purvesh; Angelo, Michael
炎症/感染
免疫/内分泌
发表日期：2022
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