日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction

CDK2抑制剂BLU-222通过诱导p21/p27与CDK4/6抑制剂协同作用，治疗耐药性乳腺癌。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67865-4
Luo, Linjie; Wang, Yan; Bui, Tuyen; Jiang, Xiaoting; Chen, Mei-Kuang; Rao, Xiayu; Mohammadhosseinpour, Sepideh; Li, Mi; Kim, Serena; Kim, Rachel Y; Kamaliasl, Saba; Ulizio, Carmen W; Tsavachidis, Spyros; Navarro-Yepes, Juliana; Kettner, Nicole M; Wingate, Hannah; Meric-Bernstam, Funda; Hunt, Kelly K; Wang, Jing; Faia, Kerrie; Keyomarsi, Khandan
CDK4
肿瘤
肿瘤免疫
治疗耐药
乳腺癌
CDK2
发表日期：2026
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Xiao Chai Hu Tang-derived decoction (Tung-Yi Fang) suppresses triple negative breast cancer cells in vitro and in vivo via regulating EGFR/AXL-mediated signaling

小柴胡汤（通益方）通过调节EGFR/AXL介导的信号通路，在体外和体内抑制三阴性乳腺癌细胞

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2026.1778030
Liao, Li-Lan; Lin, Zhi-Hu; Liaw, Chia-Ching; Yeh, Hsin; Wang, Wei-Hao; Chen, Yun-Chih; Lin, Yi-An; Tseng, Ai-Jung; Lin, Yu-Chun; Tsai, Wen-Hsin; Chao, Chi-Hong; Lu, Mei-Kuang; Hsu, Chung-Hua; Lin, Tung-Yi
肿瘤
肿瘤免疫
信号转导
EGF
AXL
乳腺癌
EGFR
细胞生物学
发表日期：2026
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FGFR3-induced Y158 PARP1 phosphorylation promotes PARP inhibitor resistance via BRG1/MRE11-mediated DNA repair in breast cancer models

在乳腺癌模型中，FGFR3诱导的Y158 PARP1磷酸化通过BRG1/MRE11介导的DNA修复促进PARP抑制剂耐药性

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI173757
Chen, Mei-Kuang; Yamaguchi, Hirohito; Gao, Yuan; Xia, Weiya; Chang, Jeffrey T; Hsiao, Yu-Chun; Shegute, Tewodros W; Lin, Zong-Shin; Wu, Chen-Shiou; Wang, Yu-Han; Litton, Jennifer K; Ding, Qingqing; Wei, Yongkun; Chu, Yu-Yi; Meric-Bernstam, Funda; Piwnica-Worms, Helen; Arun, Banu; Rodon Ahnert, Jordi; Liu, Jinsong; Yao, Jun; Chang, Wei-Chao; Wang, Hung-Ling; Tapia, Coya; Albarracin, Constance T; Keyomarsi, Khandan; Wang, Shao-Chun; Wang, Ying-Nai; Hortobagyi, Gabriel N; Lin, Chunru; Yang, Liuqing; Yu, Dihua; Hung, Mien-Chie
FGFR3
肿瘤
PARP1
肿瘤免疫
信号转导
乳腺癌
PARP
磷酸化
发表日期：2025
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Sprouting Enhances Submergence Tolerance in Rice by Promoting Glutathione Biosynthesis and Turnover

发芽通过促进谷胱甘肽的生物合成和周转来增强水稻的耐淹性

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox14121387
Wang, Mei; Kuang, Na; Mao, Ziyi; Zhou, Shangfeng; Liu, Zhixuan; Chen, Ke; Liu, Licheng; Xu, Jingbo; Wang, Lifeng; Lu, Haoyu
发表日期：2025
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Targeting CDK2 and other novel cell cycle targets for breast cancer therapy

以 CDK2 和其他新型细胞周期靶点为靶点的乳腺癌治疗

期刊:Expert Opinion on Therapeutic Targets
影响因子:4.4
doi:10.1080/14728222.2025.2537412
Chen, Mei-Kuang; Luo, Linjie; Massoumi, Nicole; Keyomarsi, Khandan
肿瘤
肿瘤免疫
乳腺癌
细胞生物学
CDK2
发表日期：2025
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The MaASR3-MaHDT1 module modulates high-temperature-inhibited chlorophyll breakdown in banana fruit by suppressing the E3 ligase MaNIP1

MaASR3-MaHDT1模块通过抑制E3连接酶MaNIP1来调节香蕉果实中高温抑制的叶绿素分解。

期刊:
影响因子:
doi:10.1093/hr/uhaf172
Luo, Qi; Wei, Wei; Zhang, Yu-Mei; Kuang, Jian-Fei; Chen, Jian-Ye; Lu, Wang-Jin; Cai, Zhi-Jun; Shan, Wei
发表日期：2025
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Anti-inflammatory and anticancer effects of polysaccharides from Antrodia cinnamomea : A review

牛樟芝多糖的抗炎和抗癌作用：综述

期刊:
影响因子:
doi:10.1097/JCMA.0000000000001186
Lin, Zhi-Hu; Phan, Sang-Nguyen-Cao; Tran, Diem-Ngoc-Hong; Lu, Mei-Kuang; Lin, Tung-Yi
肿瘤
肿瘤免疫
发表日期：2025
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BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers

BRCA1 介导的铁死亡双重调节使 BRCA1 缺陷型癌症易受 GPX4 和 PARP 共同抑制

期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-23-1220
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Jun Yao, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy A Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
信号转导
细胞生物学
肿瘤
WB
Human
53BP1
发表日期：2024
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Low-Molecular Weight Cyclin E Confers a Vulnerability to PKMYT1 Inhibition in Triple-Negative Breast Cancer.

低分子量细胞周期蛋白 E 使三阴性乳腺癌对 PKMYT1 抑制剂敏感

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-23-4130
Li Mi, Lulla Amriti R, Wang Yan, Tsavaschidis Spyros, Wang Fuchenchu, Karakas Cansu, Nguyen Tuyen D T, Bui Tuyen N, Pina Marc A, Chen Mei-Kuang, Mastoraki Sofia, Multani Asha S, Fowlkes Natalie W, Sahin Aysegul, Marshall C Gary, Hunt Kelly K, Keyomarsi Khandan
细胞生物学
乳腺癌
发表日期：2024
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Relationship of cancer-related fatigue with psychoneurophysiological (PNP) symptoms in breast cancer survivors

乳腺癌幸存者癌症相关疲劳与心理神经生理（PNP）症状的关系

期刊:European Journal of Oncology Nursing
影响因子:2.7
doi:10.1016/j.ejon.2023.102469
Hsiao, Chao-Pin; Von Ah, Diane; Chen, Mei-Kuang; Saligan, Leorey N
肿瘤
肿瘤免疫
乳腺癌
发表日期：2024
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