Alloreactive memory CD4 T cells promote transplant rejection by engaging DCs to induce innate inflammation and CD8 T cell priming
同种异体反应性记忆CD4 T细胞通过激活树突状细胞诱导先天性炎症和CD8 T细胞启动,从而促进移植排斥反应。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2401658121
Saha, Irene; Chawla, Amanpreet Singh; Oliveira, Ana Paula B N; Elfers, Eileen E; Warrick, Kathrynne; Meibers, Hannah E; Jain, Viral G; Hagan, Thomas; Katz, Jonathan D; Pasare, Chandrashekhar
炎症
T细胞
炎症/感染
树突状细胞
免疫排斥
CD8
T细胞
CD4
细胞生物学
树突状细胞
免疫/内分泌