日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In vitro PK/PD modeling and simulation to accurately assess the antimicrobial activity of tigecycline against Mycobacterium abscessus

体外药代动力学/药效动力学建模和模拟,以准确评估替加环素对脓肿分枝杆菌的抗菌活性

Park, Hyunseo; Maloney Norcross, Sara E; Hickey, Anthony J; Gonzalez-Juarrero, Mercedes; Meibohm, Bernd

Immunopathological outcomes are isolate dependent in chronic Mycobacterium avium complex pulmonary disease.

慢性鸟分枝杆菌复合群肺病的免疫病理结果取决于分离株。

Shaw Timothy D, Lam Ha, Dutt Taru S, Pearce Camron M, Alshiraihi Ilham, Obregon-Henao Andres, Henao-Tamayo Marcella, Maloney Norcross Sara E, Meibohm Bernd, Jackson Mary, Gonzalez-Juarrero Mercedes

Single-Dose Pharmacokinetic Assessment of TNX-102 SL (Cyclobenzaprine HCl Sublingual Tablets): Results From Randomized, Open-Label Studies in Healthy Volunteers

TNX-102 SL(盐酸环苯扎林舌下片)单剂量药代动力学评估:来自健康志愿者随机、开放标签研究的结果

Daugherty, Bruce L; Meibohm, Bernd; Sullivan, Gregory M; Gould, Errol M; Lederman, Seth

Steady-State Pharmacokinetic Properties of TNX-102 SL, a Sublingual Tablet Formulation of Cyclobenzaprine Hydrochloride (HCl), With Daily Dosing in Healthy Volunteers: A Randomized, Open-Label Trial

TNX-102 SL(盐酸环苯扎林舌下片)每日给药在健康志愿者中的稳态药代动力学特性:一项随机、开放标签试验

Sullivan, Gregory M; Meibohm, Bernd; Gould, Errol; Daugherty, Bruce L; Lederman, Seth

Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus

前药氟苯尼考胺通过固有耐药性激活,靶向脓肿分枝杆菌。

Phelps, Gregory A; Kurt, Sinem; Jenner, Alexander R; Anderson, Shelby M; Jayasinghe, Thalina D; Griffith, Elizabeth C; Thompson, Carl W; Yang, Lei; Wicki, Basil; Bright, Frederick K; Loudon, Victoria; Wright, William C; Srivastava, Ashish; Singh, Amarinder; Thalluri, Bhargavi; Park, Hyunseo; Lee, Robin B; Wright, Anna K; Grant-Chapman, Oliver; Conner, Daryl K; Troyer, Brennen T; Iverson, Amy; Ochoado, Jason; Pagala, Vishwajeeth R; Wu, Long; Byrum, Stephanie; Fu, Yingxue; Yuan, Zu-Fei; High, Anthony A; Schulthess, Bettina; Rosch, Jason W; Geeleher, Paul; Hobbie, Sven N; Boeck, Lucas; Meibohm, Bernd; Obregon-Henao, Andres; Sander, Peter; Lee, Richard E

Dosing Biologic Drugs for Patients With Obesity: One Size Does Not Fit All

肥胖患者生物制剂的剂量选择:并非一刀切

Balevic, Stephen J; Gonzalez, Daniel; Meibohm, Bernd

A Semi-Mechanistic Mathematical Model of Immune Tolerance Induction to Support Preclinical Studies of Human Monoclonal Antibodies in Rats

构建免疫耐受诱导的半机械数学模型以支持人单克隆抗体在大鼠中的临床前研究

Gupta, Paridhi; Ryman, Josiah T; Jawa, Vibha; Meibohm, Bernd

Characterization of new mouse models of acute and chronic Mycobacterium abscessus infection for antimicrobial drug screening

构建急性及慢性脓肿分枝杆菌感染的新型小鼠模型用于抗菌药物筛选

Alshiraihi, Ilham M; Lam, Ha; Troyer, Brennen T; Tran, Kristina N; Zohaib Ali, Malik; Conner, Daryl K; Godelfer, Abigail; Pearce, Camron; Jackson, Mary; Henao-Tamayo, Marcela; Norcross, Sara E Maloney; Meibohm, Bernd; Lee, Richard E; Gonzalez-Juarrero, Mercedes; Obregon-Henao, Andres

Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis

在复发性BALB/c小鼠结核病模型中,用光谱酰胺MBX-4888A替代Nix-TB方案中的利奈唑胺时,其具有杀菌活性

Peroutka-Bigus, Nathan; Scherman, Michael S; Kaya, Firat; Waidyarachchi, Samanthi L; Liu, Jiuyu; Rushefsky, Joel N; Butler, Michelle M; Bowlin, Terry; Meibohm, Bernd; Gonzalez-Juarrero, Mercedes; Lenaerts, Anne J; Zimmerman, Matthew; Lee, Richard E; Robertson, Gregory T

Broad spectrum antiviral BDGR-164 provides protection against lethal neurotropic alphavirus infection in mice

广谱抗病毒药物BDGR-164可保护小鼠免受致命性嗜神经性甲病毒感染。

Williams, Evan P; Xue, Yi; Yang, Dong; Lee, Jasper; Kim, Eunjung; Ponce-Flores, Alexander; Zalduondo, Lillian; Cao, Xufeng; Chung, Donghoon; Golden, Jennifer E; Meibohm, Bernd; Fitzpatrick, Elizabeth A; Weaver, Scott C; Jonsson, Colleen B