Discovery of novel phosphodiesterase-1 inhibitors for curing vascular dementia: Suppression of neuroinflammation by blocking NF- κ B transcription regulation and activating cAMP/CREB axis
发现用于治疗血管性痴呆的新型磷酸二酯酶-1抑制剂：通过阻断 NF- κ B 转录调控和激活 cAMP/CREB 轴来抑制神经炎症
期刊:Acta Pharmaceutica Sinica B
影响因子:14.7
doi:10.1016/j.apsb.2022.09.023
Qian Zhou, Meiling Le, Yiyi Yang, Wenjuan Wang, Yuqi Huang, Quan Wang, Yijing Tian, Meiyan Jiang, Yong Rao, Hai-Bin Luo, Yinuo Wu
信号转导
神经
神经炎症
阿尔茨海默症
ICC-IF
GPCR/Calcium/cAMP
