日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activities of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284 against the Biothreat Pathogen Bacillus anthracis and Its Type II Topoisomerases

新型细菌拓扑异构酶抑制剂OSUAB-0284对生物威胁病原体炭疽杆菌及其II型拓扑异构酶的活性

Mann, Chelsea A; Halasohoris, Stephanie A; Gray, Annette M; Chua, Jennifer; Spencer, Jade L; Curry, Bobby J; Babyak, Ashley L; Klimko, Christopher P; Cote, Christopher K; West, Jason S; Mitton-Fry, Mark J; Meinig, J Matthew; Osheroff, Neil

Efficacy evaluation of the S-adenosylhomocysteine hydrolase inhibitor MSD-914 in rhesus macaques (Macaca Mulatta) challenged with Ebola virus by the intramuscular route

对经肌肉注射途径感染埃博拉病毒的恒河猴(Macaca mulatta)进行S-腺苷高半胱氨酸水解酶抑制剂MSD-914的疗效评价

Johnston, Sara C; Ginnetti, Anthony T; Twenhafel, Nancy A; Norris, Sarah L W; Chen, Shiying; Moore, Josh L; Boyce, Christopher W; Frick, Ondraya M; Dyer, Dave N; Marsh, Donald J; Stevens, Stephen C; Knapp, Walter F; Berrier, Kerry L; Wan, Hui; Adam, Gregory C; Hartingh, Timothy J; Esham, Heather L; Fiallos, Jimmy O; Blue, Eugene L; Sifford, Willie B; Latty, Jonathan D; Mills, Harold L; Alli, Nazira A; Piper, Ashley E; Goodson, Aimee I; Meinig, J Matthew; Olsen, David B; Lieberman, Linda A; Panchal, Rekha G

In Vivo Comparison of Branched vs Linear Pegylation of a Capsule-Degrading Enzyme for Treatment of Anthrax.

炭疽治疗中,对荚膜降解酶进行支链聚乙二醇化与线性聚乙二醇化的体内比较

Chua Jennifer, Mathur Devina, Lankford Hannah, Meinig J Matthew, Chabot Donald J, Legler Patricia M, Friedlander Arthur M

An evaluation of antibiotic options for the treatment of biothreat pathogens

对治疗生物威胁病原体的抗生素方案进行评估

Meinig, J Matthew; Nelson, Michelle; Cote, Christopher K; Emmett, Stevan R; Harding, Sarah V

Virulence of Burkholderia pseudomallei ATS2021 Unintentionally Imported to United States in Aromatherapy Spray

意外通过芳香疗法喷雾剂进口到美国的类鼻疽伯克霍尔德菌 ATS2021 的毒力

Cote, Christopher K; Mlynek, Kevin D; Klimko, Christopher P; Biryukov, Sergei S; Mou, Sherry; Hunter, Melissa; Rill, Nathaniel O; Dankmeyer, Jennifer L; Miller, Jeremey A; Talyansky, Yuli; Davies, Michael L; Meinig, J Matthew; Halasohoris, Stephanie A; Gray, Anette M; Spencer, Jade L; Babyak, Ashley L; Hourihan, M Kelly; Curry, Bobby J; Toothman, Ronald G; Ruiz, Sara I; Zeng, Xiankun; Ricks, Keersten M; Clements, Tamara L; Douglas, Christina E; Ravulapalli, Suma; Stefan, Christopher P; Shoemaker, Charles J; Elrod, Mindy G; Gee, Jay E; Weiner, Zachary P; Qiu, Ju; Bozue, Joel A; Twenhafel, Nancy A; DeShazer, David

A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques

一项随机、双盲、载体对照剂量范围研究,旨在评估和表征瑞德西韦对恒河猴埃博拉病毒的疗效

Zumbrun, Elizabeth E; Garvey, Carly B; Wells, Jay B; Lynn, Ginger C; Van Tongeren, Sean A; Steffens, Jesse T; Wetzel, Kelly S; Wetzel, Darrell L; Esham, Heather L; Garza, Nicole L; Lee, Eric D; Scruggs, Jennifer L; Rossi, Franco D; Brown, Elizabeth S; Weidner, Jessica M; Gomba, Laura M; O'Brien, Kristan A; Jay, Alexandra N; Zeng, Xiankun; Akers, Kristen S; Kallgren, Paul A; Englund, Ethan; Meinig, J Matthew; Kugelman, Jeffrey R; Moore, Joshua L; Bloomfield, Holly A; Norris, Sarah L; Bryan, Tameka; Scheuerell, Christie H; Walters, Jesse; Mollova, Nevena; Blair, Christiana; Babusis, Darius; Cihlar, Tomas; Porter, Danielle P; Singh, Bali; Hedskog, Charlotte; Bavari, Sina; Warren, Travis K; Bannister, Roy

Structure-Activity Relationships of Central Nervous System Penetration by Fatty Acid Amide Hydrolase (FAAH)-Targeted Thyromimetic Prodrugs

靶向脂肪酸酰胺水解酶(FAAH)的拟甲状腺素前药穿透中枢神经系统的构效关系

Meinig, J Matthew; Ferrara, Skylar J; Banerji, Tapasree; Banerji, Tania; Sanford-Crane, Hannah S; Bourdette, Dennis; Scanlan, Thomas S

Synthesis of Fluorophores that Target Small Molecules to the Endoplasmic Reticulum of Living Mammalian Cells

合成能将小分子靶向活哺乳动物细胞内质网的荧光团

Meinig, J Matthew; Fu, Liqiang; Peterson, Blake R

Anticancer/antiviral agent Akt inhibitor-IV massively accumulates in mitochondria and potently disrupts cellular bioenergetics

抗癌/抗病毒药物Akt抑制剂-IV在细胞线粒体中大量积累,并强烈干扰细胞生物能量学。

Meinig, J Matthew; Peterson, Blake R