Meisig相关文献与解析，生知库 | 链接生命科学的每一步

High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation

通过人类神经上皮细胞和心肌细胞分化体外试验对发育毒物进行高精度分类

Florian Seidel, Anna Cherianidou, Franziska Kappenberg, Miriam Marta, Nadine Dreser, Jonathan Blum, Tanja Waldmann, Nils Blüthgen, Johannes Meisig, Katrin Madjar, Margit Henry, Tamara Rotshteyn, Andreas Scholtz-Illigens, Rosemarie Marchan, Karolina Edlund, Marcel Leist, Jörg Rahnenführer, Agapios Sa

神经

Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test

基于人类 iPSC 转录组学的测试中发育毒物的分类

期刊:Chemical Research in Toxicology

影响因子:3.7

doi:10.1021/acs.chemrestox.1c00392

Anna Cherianidou, Florian Seidel, Franziska Kappenberg, Nadine Dreser, Jonathan Blum, Tanja Waldmann, Nils Blüthgen, Johannes Meisig, Katrin Madjar, Margit Henry, Tamara Rotshteyn, Rosemarie Marchan, Karolina Edlund, Marcel Leist, Jörg Rahnenführer, Agapios Sachinidis, Jan G Hengstler

Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation

干细胞转录组动力学建模以识别正常和受干扰的神经外胚层分化的调控模块

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkaa1089

Johannes Meisig, Nadine Dreser, Marion Kapitza, Margit Henry, Tamara Rotshteyn, Jörg Rahnenführer, Jan G Hengstler, Agapios Sachinidis, Tanja Waldmann, Marcel Leist, Nils Blüthgen

The gene regulatory network of mESC differentiation: a benchmark for reverse engineering methods

mESC分化的基因调控网络：逆向工程方法的基准

期刊:Philosophical Transactions of the Royal Society B-Biological Sciences

影响因子:4.7

doi:10.1098/rstb.2017.0222

Meisig, Johannes; Blüthgen, Nils

信号转导

发表日期：2018

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An immediate-late gene expression module decodes ERK signal duration

即时晚期基因表达模块解码ERK信号持续时间

期刊:Molecular Systems Biology

影响因子:8.5

doi:10.15252/msb.20177554

Florian Uhlitz, Anja Sieber, Emanuel Wyler, Raphaela Fritsche-Guenther, Johannes Meisig, Markus Landthaler, Bertram Klinger, Nils Blüthgen

Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests

定义基于转录组的指标以定量表征化学干扰的干细胞发育：STOP-Toxukn 和 STOP-Toxukk 测试的介绍

期刊:Archives of Toxicology

影响因子:4.8

doi:10.1007/s00204-016-1741-8

Vaibhav Shinde, Lisa Hoelting, Sureshkumar Perumal Srinivasan, Johannes Meisig, Kesavan Meganathan, Smita Jagtap, Marianna Grinberg, Julia Liebing, Nils Bluethgen, Jörg Rahnenführer, Eugen Rempel, Regina Stoeber, Stefan Schildknecht, Sunniva Förster, Patricio Godoy, Christoph van Thriel, John Antony

Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

基于人类胚胎干细胞和诱导性多能干细胞的致畸转录组预测测试的比较

期刊:Stem Cell Research

影响因子:7.1

doi:10.1186/s13287-016-0449-2

Vaibhav Shinde, Sureshkumar Perumal Srinivasan, Margit Henry, Tamara Rotshteyn, Jürgen Hescheler, Jörg Rahnenführer, Marianna Grinberg, Johannes Meisig, Nils Blüthgen, Tanja Waldmann, Marcel Leist, Jan Georg Hengstler, Agapios Sachinidis

Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants

利用干细胞衍生的未成熟人背根神经节神经元鉴定周围神经毒物

期刊:Stem Cells Translational Medicine

影响因子:4.9

doi:10.5966/sctm.2015-0108

Hoelting, Lisa; Klima, Stefanie; Karreman, Christiaan; Grinberg, Marianna; Meisig, Johannes; Henry, Margit; Rotshteyn, Tamara; Rahnenführer, Jörg; Blüthgen, Nils; Sachinidis, Agapios; Waldmann, Tanja; Leist, Marcel

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

基于转录组的分类器通过干细胞测试识别发育毒物：组蛋白去乙酰化酶抑制剂的设计、验证和优化

期刊:Archives of Toxicology

影响因子:4.8

doi:10.1007/s00204-015-1573-y

Eugen Rempel, Lisa Hoelting, Tanja Waldmann, Nina V Balmer, Stefan Schildknecht, Marianna Grinberg, John Antony Das Gaspar, Vaibhav Shinde, Regina Stöber, Rosemarie Marchan, Christoph van Thriel, Julia Liebing, Johannes Meisig, Nils Blüthgen, Agapios Sachinidis, Jörg Rahnenführer, Jan G Hengstler, M

Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting

亚细胞 mRNA 动力学建模揭示核保留是限速因素

High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation

通过人类神经上皮细胞和心肌细胞分化体外试验对发育毒物进行高精度分类

Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test

基于人类 iPSC 转录组学的测试中发育毒物的分类

Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation

干细胞转录组动力学建模以识别正常和受干扰的神经外胚层分化的调控模块

The gene regulatory network of mESC differentiation: a benchmark for reverse engineering methods

mESC分化的基因调控网络：逆向工程方法的基准

An immediate-late gene expression module decodes ERK signal duration

即时晚期基因表达模块解码ERK信号持续时间

Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests

定义基于转录组的指标以定量表征化学干扰的干细胞发育：STOP-Toxukn 和 STOP-Toxukk 测试的介绍

Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

基于人类胚胎干细胞和诱导性多能干细胞的致畸转录组预测测试的比较

Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants

利用干细胞衍生的未成熟人背根神经节神经元鉴定周围神经毒物

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

基于转录组的分类器通过干细胞测试识别发育毒物：组蛋白去乙酰化酶抑制剂的设计、验证和优化