日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Regulation of Gene Expression of phiEco32-like Bacteriophage 7-11

phiEco32样噬菌体7-11的基因表达调控

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v14030555
Lavysh, Daria; Mekler, Vladimir; Klimuk, Evgeny; Severinov, Konstantin
信号转导
发表日期：2022
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Novel Escherichia coli RNA Polymerase Binding Protein Encoded by Bacteriophage T5.

由噬菌体T5编码的新型大肠杆菌RNA聚合酶结合蛋白

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v12080807
Klimuk Evgeny, Mekler Vladimir, Lavysh Darya, Serebryakova Marina, Akulenko Natalia, Severinov Konstantin
免疫/内分泌
发表日期：2020
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CRISPR-Cas molecular beacons as tool for studies of assembly of CRISPR-Cas effector complexes and their interactions with DNA

CRISPR-Cas分子信标作为研究CRISPR-Cas效应复合物组装及其与DNA相互作用的工具

期刊:Methods in Enzymology
影响因子:
doi:10.1016/bs.mie.2018.10.026
Mekler, Vladimir; Kuznedelov, Konstantin; Minakhin, Leonid; Murugan, Karthik; Sashital, Dipali G; Severinov, Konstantin
发表日期：2019
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Mechanism of duplex DNA destabilization by RNA-guided Cas9 nuclease during target interrogation

RNA引导的Cas9核酸酶在靶标识别过程中破坏双链DNA稳定性的机制

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1619926114
Mekler, Vladimir; Minakhin, Leonid; Severinov, Konstantin
发表日期：2017
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RNA polymerase molecular beacon as tool for studies of RNA polymerase-promoter interactions.

RNA聚合酶分子信标作为研究RNA聚合酶-启动子相互作用的工具

期刊:Methods
影响因子:4.3
doi:10.1016/j.ymeth.2015.04.033
Mekler Vladimir, Severinov Konstantin
免疫/内分泌
发表日期：2015
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GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides

GE23077 与 RNA 聚合酶的“i”和“i+1”位点结合，阻止起始核苷酸的结合。

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.02450
Zhang, Yu; Degen, David; Ho, Mary X; Sineva, Elena; Ebright, Katherine Y; Ebright, Yon W; Mekler, Vladimir; Vahedian-Movahed, Hanif; Feng, Yu; Yin, Ruiheng; Tuske, Steve; Irschik, Herbert; Jansen, Rolf; Maffioli, Sonia; Donadio, Stefano; Arnold, Eddy; Ebright, Richard H
发表日期：2014
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Cooperativity and interaction energy threshold effects in recognition of the -10 promoter element by bacterial RNA polymerase.

细菌 RNA 聚合酶识别 -10 启动子元件的协同性和相互作用能量阈值效应

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkt541
Mekler Vladimir, Severinov Konstantin
微生物学
发表日期：2013
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Structural and mechanistic basis for the inhibition of Escherichia coli RNA polymerase by T7 Gp2.

T7 Gp2抑制大肠杆菌RNA聚合酶的结构和机制基础

期刊:Molecular Cell
影响因子:16.6
doi:10.1016/j.molcel.2012.06.013
James Ellen, Liu Minhao, Sheppard Carol, Mekler Vladimir, Cámara Beatriz, Liu Bing, Simpson Pete, Cota Ernesto, Severinov Konstantin, Matthews Steve, Wigneshweraraj Sivaramesh
微生物学
发表日期：2012
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Interaction of Escherichia coli RNA polymerase σ70 subunit with promoter elements in the context of free σ70, RNA polymerase holoenzyme, and the β'-σ70 complex

在游离σ70、RNA聚合酶全酶和β'-σ70复合物的背景下，大肠杆菌RNA聚合酶σ70亚基与启动子元件的相互作用

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M110.174102
Mekler, Vladimir; Pavlova, Olga; Severinov, Konstantin
发表日期：2011
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Distance-restrained docking of rifampicin and rifamycin SV to RNA polymerase using systematic FRET measurements: developing benchmarks of model quality and reliability

利用系统性的FRET测量方法，对利福平和利福霉素SV与RNA聚合酶进行距离约束对接：建立模型质量和可靠性的基准

期刊:Biophysical Journal
影响因子:3.1
doi:10.1529/biophysj.104.050187
Knight, Jennifer L; Mekler, Vladimir; Mukhopadhyay, Jayanta; Ebright, Richard H; Levy, Ronald M
RET
发表日期：2005
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