日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Accessibility at a primed distal Fshb-Kcna4 super-enhancer is facilitated by Foxl2 during gonadotrope differentiation.

在促性腺激素分化过程中,Foxl2 促进了远端 Fshb-Kcna4 超级增强子的可及性。

Refael Tal, Golan Gil, Darsa Daniella, Pnueli Lilach, Chakravarty Probir, Rizzoti Karine, Melamed Philippa

Gonadotrophs have a dual origin, with most derived from early postnatal pituitary stem cells.

促性腺激素细胞具有双重起源,其中大多数来源于出生后早期的垂体干细胞

Sheridan Daniel, Chakravarty Probir, Golan Gil, Shiakola Yiolanda, Olsen Jessica, Burnett Elise, Galichet Christophe, Fiordelisio Tatiana, Mollard Patrice, Melamed Philippa, Lovell-Badge Robin, Rizzoti Karine

High-throughput transcriptome analysis reveals a developmental increase in Acvr1c which mediates epigenetic repression of the gene encoding the pubertal brake, Makorin ring finger protein 3.

高通量转录组分析揭示了 Acvr1c 的发育增加,它介导了青春期刹车基因 Makorin 环指蛋白 3 的表观遗传抑制。

Shalev Dor, Golan Gil, Pnueli Lilach, Kahan Anat, Mandel-Gutfreund Yael, Melamed Philippa

Association of childhood dehydroepiandrosterone sulfate concentration, pubertal development, and DNA methylation at puberty-related genes

儿童期脱氢表雄酮硫酸酯浓度、青春期发育和青春期相关基因的DNA甲基化之间的关联

Sudman, Maya; Stöger, Reinhard; Bentley, Gillian R; Melamed, Philippa

Long Noncoding RNAs Expressed in Mouse Pituitary Development and Mature Hormone-Producing Cells

小鼠垂体发育和成熟激素分泌细胞中表达的长链非编码RNA

Brinkmeier, Michelle Lynn; George, Akima Semone; Cheung, Leonard Yan Ming; Mills, Ryan Edward; Melamed, Philippa; Camper, Sally Ann

Erythropoietin-producing hepatocellular receptor B6 is highly expressed in non-functioning pituitary neuroendocrine tumors and its expression correlates with tumor size

红细胞生成素生成肝细胞受体B6在无功能性垂体神经内分泌肿瘤中高表达,且其表达与肿瘤大小相关。

Rubinfeld, Hadara; Cohen, Zvi R; Bendavid, Uzi; Fichman-Horn, Suzana; Levy-Barda, Adva; David, Cfir; Melamed, Philippa; Shimon, Ilan

Childhood environment influences epigenetic age and methylation concordance of a CpG clock locus in British-Bangladeshi migrants

童年环境影响英国-孟加拉移民中CpG时钟位点的表观遗传年龄和甲基化一致性

Stöger, Reinhard; Choi, Minseung; Begum, Khurshida; Leeman, Gregory; Emes, Richard D; Melamed, Philippa; Bentley, Gillian R

Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing.

5α还原酶-1的表观遗传调控是生殖功能和青春期发育时间适应性可塑性的基础

Bar-Sadeh Ben, Amichai Or E, Pnueli Lilach, Begum Khurshida, Leeman Gregory, Emes Richard D, Stöger Reinhard, Bentley Gillian R, Melamed Philippa

Single molecule characterization of the binding kinetics of a transcription factor and its modulation by DNA sequence and methylation

转录因子结合动力学的单分子表征及其受DNA序列和甲基化调控

Khamis, Hadeel; Rudnizky, Sergei; Melamed, Philippa; Kaplan, Ariel

Enhancing Gonadotrope Gene Expression Through Regulatory lncRNAs

通过调控性lncRNA增强促性腺激素细胞基因表达

Refael, Tal; Melamed, Philippa