日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Exploration of a benzothiophene scaffold for use as adjuvants with β-lactam antibiotics against methicillin-resistant Staphylococcus aureus

探索苯并噻吩骨架作为β-内酰胺类抗生素佐剂对抗耐甲氧西林金黄色葡萄球菌

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d5md01109d
Stefaniak, Monica A; Gondil, Vijay S; Gillis, Emily P; Nemeth, Ansley M; Oliver, Allen G; Melander, Roberta J; Dunman, Paul M; Melander, Christian
发表日期：2026
文献求助 收藏

Mechanisms of antibiofilm compounds JG-1 and M4 across multiple species: alterations of protein interactions essential to biofilm formation

抗生物膜化合物JG-1和M4在多种物种中的作用机制：改变对生物膜形成至关重要的蛋白质相互作用

期刊:Frontiers in Cellular and Infection Microbiology
影响因子:4.8
doi:10.3389/fcimb.2025.1631575
Bennett, Aliyah N; Maziarz, Jacob F; Laipply, Baileigh; Cole, Allysa L; Woolard, Katherine J; Sorge, Amy; Zeiler, Michael J; Melander, Roberta J; Melander, Christian; Gunn, John S
微生物学
发表日期：2025
文献求助 收藏

2‑Aminoimidazole-benzimidazole Conjugates Potentiate the Gram-Positive Selective Antibiotic Clarithromycin against Acinetobacter baumannii

2-氨基咪唑-苯并咪唑缀合物可增强革兰氏阳性选择性抗生素克拉霉素对鲍曼不动杆菌的抗菌活性

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5c00201
Crotteau, Ashley N; Nemeth, Ansley M; Melander, Roberta J; Melander, Christian
发表日期：2025
文献求助 收藏

Validation of a Cystic Fibrosis Co-Culture Model for the Identification of Dual Acting Compounds with Antibiotic and Antibiotic Adjuvant Properties

验证囊性纤维化共培养模型在鉴定具有抗生素和抗生素佐剂特性的双效化合物中的应用

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.5c00226
Mattingly, Anne E; Li, Haoting; Melander, Roberta J; Melander, Christian
发表日期：2025
文献求助 收藏

Phenyl urea based adjuvants for β-lactam antibiotics against methicillin resistant Staphylococcus aureus

苯脲类佐剂用于β-内酰胺类抗生素对抗耐甲氧西林金黄色葡萄球菌

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2025.130164
Butman, Hailey S; Stefaniak, Monica A; Walsh, Danica J; Gondil, Vijay S; Young, Mikaeel; Crow, Andrew H; Nemeth, Ansley M; Melander, Roberta J; Dunman, Paul M; Melander, Christian
发表日期：2025
文献求助 收藏

Adjuvants restore colistin sensitivity in mouse models of highly colistin-resistant isolates, limiting bacterial proliferation and dissemination

佐剂可恢复小鼠模型中高度耐粘菌素菌株对粘菌素的敏感性，从而限制细菌的增殖和扩散。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00671-24
Koller, Beverly H; Jania, Leigh A; Li, Haoting; Barker, William T; Melander, Roberta J; Melander, Christian
微生物学
发表日期：2024
文献求助 收藏

Synthesis, Stereochemical Resolution, and Analogue Synthesis of Variabiline, an Aporphine Alkaloid That Sensitizes Acinetobacter baumannii and Klebsiella pneumoniae to Colistin

合成、立体化学拆分及类似物合成Variabiline（一种阿朴啡生物碱，可增强鲍曼不动杆菌和肺炎克雷伯菌对粘菌素的敏感性）

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.4c00026
Li, Haoting; Nemeth, Ansley M; Melander, Roberta J; Melander, Christian
肺炎
发表日期：2024
文献求助 收藏

Identification of a 2-Aminobenzimidazole Scaffold that Potentiates Gram-Positive Selective Antibiotics Against Gram-Negative Bacteria

鉴定一种能增强革兰氏阳性选择性抗生素对革兰氏阴性菌活性的2-氨基苯并咪唑骨架

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.202400127
Nemeth, Ansley M; Young, Milah M; Melander, Roberta J; Smith, Richard D; Ernst, Robert K; Melander, Christian
发表日期：2024
文献求助 收藏

Development of phenyl-urea-based small molecules that target penicillin-binding protein 4

开发靶向青霉素结合蛋白4的苯脲类小分子

期刊:
影响因子:
doi:10.1111/cbdd.14569
Gondil, Vijay S; Butman, Hailey S; Young, Mikaeel; Walsh, Danica J; Narkhede, Yogesh; Zeiler, Michael J; Crow, Andrew H; Carpenter, Morgan E; Mardikar, Aashay; Melander, Roberta J; Wiest, Olaf; Dunman, Paul M; Melander, Christian
发表日期：2024
文献求助 收藏

Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator

小分子通过靶向保守反应调节因子减弱细菌毒力

期刊:mBio
影响因子:4.7
doi:10.1128/mbio.00137-23
Liu, Chang; Zhang, Hua; Peng, Xian; Blackledge, Meghan S; Furlani, Robert E; Li, Haoting; Su, Zhaoming; Melander, Roberta J; Melander, Christian; Michalek, Suzanne; Wu, Hui
微生物学
发表日期：2023
文献求助 收藏