日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An approach to characterize mechanisms of action of anti-amyloidogenic compounds in vitro and in situ.

一种表征抗淀粉样蛋白化合物在体外和体内作用机制的方法

Stalder P, Serdiuk T, Ghosh D, Fleischmann Y, Ait-Bouziad N, Quast J-P, Malinovska L, Ouared A, Davranche A, Haenseler W, Boudou C, Tsika E, Stöhr J, Melki R, Riek R, de Souza N, Picotti P

CYP1B1 mutations in French patients with early-onset primary open-angle glaucoma

法国早发性原发性开角型青光眼患者的CYP1B1基因突变

Melki, R; Colomb, E; Lefort, N; Brézin, A P; Garchon, H-J

The M98K variant of the OPTINEURIN (OPTN) gene modifies initial intraocular pressure in patients with primary open angle glaucoma

视神经蛋白(OPTN)基因的M98K变异会改变原发性开角型青光眼患者的初始眼内压。

Melki, R; Belmouden, A; Akhayat, O; Brézin, A; Garchon, H-J

A novel cochaperonin that modulates the ATPase activity of cytoplasmic chaperonin

一种新型辅助伴侣蛋白,可调节胞质伴侣蛋白的ATPase活性

Gao, Y; Melki, R; Walden, P D; Lewis, S A; Ampe, C; Rommelaere, H; Vandekerckhove, J; Cowan, N J

Facilitated folding of actins and tubulins occurs via a nucleotide-dependent interaction between cytoplasmic chaperonin and distinctive folding intermediates

肌动蛋白和微管蛋白的折叠是通过胞质伴侣蛋白与特定折叠中间体之间依赖于核苷酸的相互作用而实现的。

Melki, R; Cowan, N J

Eukaryotic cytosolic chaperonin contains t-complex polypeptide 1 and seven related subunits

真核细胞胞质伴侣蛋白包含t复合物多肽1和七个相关亚基

Rommelaere, H; Van Troys, M; Gao, Y; Melki, R; Cowan, N J; Vandekerckhove, J; Ampe, C