日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combining the constitutive TRAIL-secreting induced neural stem cell therapy with the novel anti-cancer drug TR-107 in glioblastoma

组成型TRAIL分泌诱导神经干细胞疗法与新型抗癌药物TR-107联合治疗胶质母细胞瘤

Morrent Thang, Clara Mellows, Lauren E Kass, Sabrina Daglish, Emily M J Fennell, Breanna E Mann, Alison R Mercer-Smith, Alain Valdivia, Lee M Graves, Shawn D Hingtgen

Current approaches in enhancing TRAIL therapies in glioblastoma

目前增强胶质母细胞瘤TRAIL疗法的研究方向

Thang, Morrent; Mellows, Clara; Mercer-Smith, Alison; Nguyen, Phuong; Hingtgen, Shawn

Large epigenome-wide association study identifies multiple novel differentially methylated CpG sites associated with suicidal thoughts and behaviors in veterans

一项大规模的全基因组关联研究发现,退伍军人中存在多个与自杀念头和行为相关的新型差异甲基化CpG位点。

Kimbrel, Nathan A; Garrett, Melanie E; Evans, Mariah K; Mellows, Clara; Dennis, Michelle F; Hair, Lauren P; Hauser, Michael A; Ashley-Koch, Allison E; Beckham, Jean C

M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer

M1hot肿瘤相关巨噬细胞促进组织驻留记忆T细胞在人肺癌中的浸润和存活

Eva M Garrido-Martin ,Toby W P Mellows ,James Clarke ,Anusha-Preethi Ganesan ,Oliver Wood ,Angelica Cazaly ,Gregory Seumois ,Serena J Chee ,Aiman Alzetani ,Emma V King ,Catherine C Hedrick ,Gareth Thomas ,Peter S Friedmann ,Christian Hermann Ottensmeier ,Pandurangan Vijayanand # ,Tilman Sanchez-Elsner #

Chemotherapy-induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol

化疗引起的恶病质会扰乱下丘脑和全身脂胺的平衡,而大麻酚可以减轻这种症状。

Brierley, Daniel I; Harman, Joe R; Giallourou, Natasha; Leishman, Emma; Roashan, Anna Emily; Mellows, Ben A D; Bradshaw, Heather B; Swann, Jonathan R; Patel, Ketan; Whalley, Benjamin J; Williams, Claire M

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

脂肪间充质干细胞分泌蛋白组通过细胞外囊泡货物和可溶性蛋白质的协同作用促进骨骼肌再生

Robert Mitchell, Ben Mellows, Jonathan Sheard, Manuela Antonioli, Oliver Kretz, David Chambers, Marie-Theres Zeuner, James E Tomkins, Bernd Denecke, Luca Musante, Barbara Joch, Florence Debacq-Chainiaux, Harry Holthofer, Steve Ray, Tobias B Huber, Joern Dengjel, Paolo De Coppi, Darius Widera, Ketan

Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease

蛇毒金属蛋白酶诱导永久性肌肉损伤的机制

Williams, Harry F; Mellows, Ben A; Mitchell, Robert; Sfyri, Peggy; Layfield, Harry J; Salamah, Maryam; Vaiyapuri, Rajendran; Collins-Hooper, Henry; Bicknell, Andrew B; Matsakas, Antonios; Patel, Ketan; Vaiyapuri, Sakthivel

Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology

结核分枝杆菌破坏人类巨噬细胞中的负调节途径以驱动免疫病理学

Patience T Brace, Liku B Tezera, Magdalena K Bielecka, Toby Mellows, Diana Garay, Shuye Tian, Lucinda Rand, Justin Green, Sanjay Jogai, Andrew J Steele, Timothy M Millar, Tilman Sanchez-Elsner, Jon S Friedland, Christopher G Proud, Paul T Elkington

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch.

胰腺癌中αvβ6整合素的促迁移和TGF-β激活功能通过Eps8依赖的GTP酶开关进行差异性调节

Tod Jo, Hanley Christopher J, Morgan Mark R, Rucka Marta, Mellows Toby, Lopez Maria-Antoinette, Kiely Philip, Moutasim Karwan A, Frampton Steven J, Sabnis Durgagauri, Fine David R, Johnson Colin, Marshall John F, Scita Giorgio, Jenei Veronika, Thomas Gareth J

Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis

诱导成纤维细胞衰老会产生非纤维化肌成纤维细胞表型,对癌症预后产生不同的影响

Massimiliano Mellone, Christopher J Hanley, Steve Thirdborough, Toby Mellows, Edwin Garcia, Jeongmin Woo, Joanne Tod, Steve Frampton, Veronika Jenei, Karwan A Moutasim, Tasnuva D Kabir, Peter A Brennan, Giulia Venturi, Kirsty Ford, Nicolas Herranz, Kue Peng Lim, James Clarke, Daniel W Lambert, Steph