日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epigenetic Regulation of Chromosomal Instability by EZH2 Methyltransferase.

EZH2甲基转移酶对染色体不稳定性进行表观遗传调控。

Bai Yang, Agustinus Albert S, Yomtoubian Shira, Meydan Cem, McNally Dylan R, Yoffe Liron, Hubisz Melissa J, Tranquille Marvel, Pramod Sneha, Hong Christy, Plasilova Magdalena L, Kapoor Aakanksha R, Singh Arshdeep, Withers Henry, Dow Lukas E, Laughney Ashley M, Bhinder Bhavneet, Elemento Olivier, Melnick Ari M, Bakhoum Samuel F, Mittal Vivek

T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response.

在体液免疫反应过程中,滤泡辅助性T细胞可短暂地激活生发中心B细胞的可塑性状态。

Scourzic Laurianne, Izzo Franco, Teater Matt, Polyzos Alexander P, Cucereavii Lucretia, Chin Christopher R, Papin Antonin, Pinto Hugo B, Mlynarczyk Coraline, Tsialta Ioanna, Xia Min, Lidoski Abigail, Myers Robert M, Israel Eva M, Venturutti Leandro, Mackay Simon P, Hoehn Kenneth B, Skoultchi Arthur I, Béguelin Wendy, Stadtfeld Matthias, Chen Zhengming, Landau Dan A, Melnick Ari M, Apostolou Effie

Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the Nfkbia-c-Rel axis

Tet2 缺陷通过 Nfkbia-c-Rel 轴的失调促进 IgG1+ B 细胞扩增和分化阻滞

Ghamlouch, Hussein; Degaud, Michaël; Della-Valle, Veronique; Eeckhoutte, Alexandre; Armand, Marine; Joudat, Amina; Decaudin, Camille; Dominguez, Pilar M; Rosikiewicz, Wojciech; Pawlikowska, Patrycja; Darwiche, Walaa; Mouly, Enguerran; Li, Sheng; Melnick, Ari M; Aoufouchi, Said; Bernard, Olivier A

The hematopoietic stem cell MYB enhancer is essential for and recurrently amplified during T cell leukemogenesis

造血干细胞MYB增强子对于T细胞白血病的发生至关重要,并在T细胞白血病发生过程中反复扩增。

Mullin, Carea; Lin, Karena; Choe, Elizabeth; Sha, Cher; Shukla, Zeel; Campbell, Koral; McCarter, Anna C; Wang, Annie; Nieves-Salva, Jannaldo; Khan, Sarah; Keeley, Theresa M; Liang, Shannon; Wang, Qing; Melnick, Ashley F; Evans, Pearl; Monovich, Alexander C; Iyer, Ashwin; Kodgule, Rohan; Deng, Yamei; da Veiga Leprevost, Felipe; Barnett, Kelly R; Pölönen, Petri; Khoriaty, Rami; Savic, Daniel; Teachey, David T; Mullighan, Charles G; Cieslik, Marcin; Nesvizhskii, Alexey I; Samuelson, Linda C; Jones, Morgan; Li, Qing; Ryan, Russell Jh; Chiang, Mark Y

Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification

表观遗传启动促进酪氨酸激酶抑制剂耐药性和癌基因扩增

Rebecca M Starble #,Eric G Sun #,Rana Gbyli,Jonathan Radda,Jiuwei Lu,Tyler B Jensen,Ning Sun,Nelli Khudaverdyan,Ting Zhao,Bomiao Hu,Mary Ann Melnick,Shuai Zhao,Nitin Roper,Gang Greg Wang,Alan J Tackett,Yinsheng Wang,Jikui Song,Katerina Politi,Siyuan Wang,Andrew Z Xiao

Wild-type p53 overexpression in NPM1-mutated acute myeloid leukemia: potential implications for disease biology and therapy response

NPM1突变型急性髓系白血病中野生型p53的过表达:对疾病生物学和治疗反应的潜在影响

Barone, Paul D; Dzedzik, Siarhei; Kleinman, Ashley S; Chin, Christopher R; Meydan, Cem; Valencia, Itzel; Sugita, Mayumi; Guzman, Monica L; Fein, Joshua A; Kaner, Justin D; Desai, Pinkal; Roboz, Gail J; Melnick, Ari M; Mason, Christopher E; Patel, Sanjay S

Separating tectonic and climate signals in Holocene sea-level records using marine terraces in central Chile

利用智利中部海蚀阶地分离全新世海平面记录中的构造和气候信号

Melnick, Daniel; Jara-Muñoz, Julius; Garrett, Ed; Plissart, Gaëlle; Freisleben, Roland; Strecker, Manfred R

Randomized study of the efficacy, safety, and pharmacokinetics of SPR720 for the treatment of Mycobacterium avium complex pulmonary disease

一项随机研究评估了SPR720治疗鸟分枝杆菌复合群肺病的疗效、安全性和药代动力学。

Ussery, Xilla T; Bhatt, Nivedita; Critchley, Ian A; Wong, Shekman L; Pottage, John C Jr; Melnick, David; Hamed, Kamal A

Electronic health record use factors linked to efficiency and productivity: an explainable machine learning analysis

电子健康记录使用因素与效率和生产力之间的关联:一种可解释的机器学习分析

Li, Huan; Khanna, Varada V; Apathy, Nate; Holmgren, A Jay; Loza, Andrew J; Melnick, Edward R

Developmental Nicotine Exposure Induces Intergenerational Transmission of an Ensemble of Neurodevelopmental Disorder-Related Translatomic Perturbations in DRD1-Expressing Striatal Cells of Adolescent Male Mice

发育期尼古丁暴露可诱导青春期雄性小鼠纹状体DRD1表达细胞中一系列与神经发育障碍相关的翻译扰动发生代际传递

Buck, Jordan M; Melnick, Marko; Stitzel, Jerry A