日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gene expression differences associated with alcohol use disorder in human brain

人类大脑中与酒精使用障碍相关的基因表达差异

Willis, Caryn; White, Julie D; Minto, Melyssa S; Quach, Bryan C; Han, Shizhong; Tao, Ran; Shin, Joo Heon; Deep-Soboslay, Amy; Hyde, Thomas M; Mayfield, R Dayne; Webb, Bradley T; Johnson, Eric O; Kleinman, Joel E; Bierut, Laura J; Hancock, Dana B

Identifying compounds to treat opiate use disorder by leveraging multi-omic data integration and multiple drug repurposing databases

利用多组学数据整合和多个药物再利用数据库,筛选治疗阿片类药物使用障碍的化合物

Stratford, Jeran K; Carnes, Megan Ulmer; Willis, Caryn; Minto, Melyssa S; Elnimeiry, Logain; Mathur, Ravi; Schu, Matthew; Quach, Bryan C; Carter, Javan; Nolen, Tracy; Vandergrift, Nathan; Kosten, Thomas R; Johnson, Eric Otto; Webb, Bradley T

Omics Integration Uncovers Mechanisms Associated with HIV Viral Load and Potential Therapeutic Insights

组学整合揭示与 HIV 病毒载量相关的机制及潜在治疗见解

Sullivan, Kyle A; Minto, Melyssa S; Zhang, Xinyu; Carr, William; Quach, Bryan C; Willis, Caryn; Townsend, Alice; Kruse, Peter; Lane, Matthew; Morgan, Richard; Xu, Ke; Aouizerat, Bradley E; Hancock, Dana B; Jacobson, Daniel A; Johnson, Eric O

Genome binding properties of Zic transcription factors underlie their changing functions during neuronal maturation

Zic转录因子的基因组结合特性决定了它们在神经元成熟过程中功能的变化。

Minto, Melyssa S; Sotelo-Fonseca, Jesús Emiliano; Ramesh, Vijyendra; West, Anne E

Identifying novel gene dysregulation associated with opioid overdose death: A meta-analysis of differential gene expression in human prefrontal cortex

识别与阿片类药物过量死亡相关的新型基因失调:人类前额叶皮层差异基因表达的荟萃分析

Carter, Javan K; Quach, Bryan C; Willis, Caryn; Minto, Melyssa S; Hancock, Dana B; Montalvo-Ortiz, Janitza; Corradin, Olivia; Logan, Ryan W; Walss-Bass, Consuelo; Maher, Brion S; Johnson, Eric Otto

Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics

有丝分裂后 H3K27me3 分布的双向调节是小脑颗粒神经元成熟动力学的基础

Vijyendra Ramesh #, Fang Liu #, Melyssa S Minto, Urann Chan, Anne E West

LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance

LIN9 和 NEK2 是有丝分裂保真度的核心调节因子,可通过治疗靶向治疗来克服紫杉烷耐药性

Melyssa S Roberts, Jennifer M Sahni, Morgan S Schrock, Katrina M Piemonte, Kristen L Weber-Bonk, Darcie D Seachrist, Stefanie Avril, Lindsey J Anstine, Salendra Singh, Steven T Sizemore, Vinay Varadan, Matthew K Summers, Ruth A Keri

KLF4 defines the efficacy of the epidermal growth factor receptor inhibitor, erlotinib, in triple-negative breast cancer cells by repressing the EGFR gene

KLF4 通过抑制 EGFR 基因来定义表皮生长因子受体抑制剂厄洛替尼对三阴性乳腺癌细胞的疗效

Melyssa S Roberts, Lindsey J Anstine, Viviane S Finke, Benjamin L Bryson, Bryan M Webb, Kristen L Weber-Bonk, Darcie D Seachrist, Parth R Majmudar, Ruth A Keri

Targeting BCL-xL improves the efficacy of bromodomain and extra-terminal protein inhibitors in triple-negative breast cancer by eliciting the death of senescent cells

靶向 BCL-xL 可诱导衰老细胞死亡,从而提高溴结构域和末端外蛋白抑制剂对三阴性乳腺癌的疗效

Sylvia S Gayle, Jennifer M Sahni, Bryan M Webb, Kristen L Weber-Bonk, Melyssa S Shively, Raffaella Spina, Eli E Bar, Mathew K Summers, Ruth A Keri