日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatial single-cell multiomics reveals peripheral immune dysfunction in Parkinson's and inflammatory bowel disease

空间单细胞多组学揭示帕金森病和炎症性肠病中的外周免疫功能障碍

Bolen, MacKenzie L; Buendia, Marc; Shi, Ji; Staley, Hannah; Kachergus, Jennifer M; Efron, Philip A; Park, Gwoncheol; Nagpal, Ravinder; Alvarez, Stephan D; Xue, Qing-Shan; McFarland, Nikolaus R; Zimmermann, Ellen M; Forsmark, Christopher E; Menees, Kelly B; Salas, Azucena; Aubrey Thompson, E; Tansey, Malú Gámez

Spatial Analysis of Intraductal Papillary Mucinous Neoplasms Defines a Paradoxical Keratin 17-positive, Low-grade Epithelial Population Harboring Malignant Features

导管内乳头状黏液性肿瘤的空间分析揭示了一种矛盾的角蛋白17阳性、低级别上皮细胞群,该细胞群具有恶性特征。

Li, Jay; Branch, Georgina; Macchia, Justin; Elhossiny, Ahmed M; Arya, Nandini; Liang, Julia; Kadiyala, Padma; Peterson, Nicole; Kwon, Richard; Machicado, Jorge D; Wamsteker, Erik-Jan; Schulman, Allison; Philips, George; Menees, Stacy; Xia, Jonathan; Singhi, Aatur D; Sahai, Vaibhav; Fang, Jiayun M; Frankel, Timothy L; Bednar, Filip; Pasca di Magliano, Marina; Shi, Jiaqi; Carpenter, Eileen S

RGS10 differentially modulates NFKB subunit transcription and inflammatory cytokine profiles in peritoneal macrophages

RGS10差异性地调节腹膜巨噬细胞中NFKB亚基的转录和炎症细胞因子谱

Posey, Janna E Jernigan; Dheeravath, Kruthika; Cole, Cassandra L; Neighbarger, Noelle K; Menees, Kelly B; Tansey, Malú Gámez

Cluster Analysis of Fecal Incontinence Symptoms: Associations With Anorectal Physiology and Quality of Life

粪便失禁症状的聚类分析:与肛门直肠生理和生活质量的关联

Butt, Mohsin F; Rao, Satish S C; Meyer, Isuzu; Chey, William D; Whitehead, William E; Richter, Holly E; Menees, Stacy B; Busby-Whitehead, Jan; Lamichhane, Ramesh; Chen, Jun; Hamilton, Frank A; Bharucha, Adil E

RGS10 attenuates systemic immune dysregulation induced by chronic inflammatory stress

RGS10可减轻慢性炎症应激引起的全身免疫失调

Janna E Jernigan ,Hannah A Staley ,Zachary Baty ,MacKenzie L Bolen ,Beatriz Nuñes Gomes ,Jenny Holt ,Cassandra L Cole ,Noelle K Neighbarger ,Kruthika Dheeravath ,Andrea R Merchak ,Kelly B Menees ,Stephen A Coombes ,Malú Gámez Tansey

Iron mishandling in the brain and periphery in Parkinson's disease

帕金森病中大脑和外周的铁代谢异常

Bolen, MacKenzie L; Menees, Kelly B; Dupreez, Aidan C; Tansey, Malú Gámez

MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulation

MHCII 减少不足以保护小鼠免受 α-突触核蛋白诱导的退行性变,帕金森病 HLA 位点表现出表观遗传调控。

Elizabeth M Kline ,Janna E Jernigan ,Christopher D Scharer ,Jeffrey Maurer ,Sakeenah L Hicks ,Mary K Herrick ,Rebecca L Wallings ,Sean D Kelly ,Jianjun Chang ,Kelly B Menees ,Nikolaus R McFarland ,Jeremy M Boss ,Malú Gámez Tansey ,Valerie Joers

Single-cell multiomics identifies both shared and unique features of immune dysfunction in Parkinson's disease and inflammatory bowel disease colon, plasma and stool

单细胞多组学分析揭示了帕金森病和炎症性肠病结肠、血浆和粪便中免疫功能障碍的共同特征和独特特征

Bolen, MacKenzie L; Buendia, Marc; Shi, Ji; Staley, Hannah; Kachergus, Jennifer M; Efron, Philip A; Park, Gwoncheol; Nagpal, Ravinder; Alvarez, Stephan D; Xue, Qing-Shan; McFarland, Nikolaus R; Zimmermann, Ellen M; Forsmark, Christopher E; Menees, Kelly B; Salas, Azucena; Thompson, E Aubrey; Tansey, Malú Gámez

Multiplex digital spatial profiling identifies subregion dependent targeted proteome changes across variants of dementia

多重数字空间分析可识别痴呆症不同变体中亚区域依赖性的靶向蛋白质组变化

Bolen, MacKenzie L; Menees, Kelly B; Gearing, Marla; Gong, Jingjing; Ren, Yuqi; Merchak, Andrea R; Murray, Melissa E; McEachin, Zachary T; Tansey, Malú Gámez

MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulation.

MHCII 减少不足以保护小鼠免受 α-突触核蛋白诱导的退化,帕金森病 HLA 位点表现出表观遗传调控

Kline Elizabeth M, Jernigan Janna E, Scharer Christopher D, Maurer Jeffrey, Hicks Sl Sakeenah, Herrick M Mary K, Wallings Rebecca L, Kelly Sean D, Chang Jianjun, Menees Kelly B, McFarland Nikolaus R, Boss Jeremy M, Tansey Malú Gámez, Joers Valerie