日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatial single-cell multiomics reveals peripheral immune dysfunction in Parkinson's and inflammatory bowel disease

空间单细胞多组学揭示帕金森病和炎症性肠病中的外周免疫功能障碍

Bolen, MacKenzie L; Buendia, Marc; Shi, Ji; Staley, Hannah; Kachergus, Jennifer M; Efron, Philip A; Park, Gwoncheol; Nagpal, Ravinder; Alvarez, Stephan D; Xue, Qing-Shan; McFarland, Nikolaus R; Zimmermann, Ellen M; Forsmark, Christopher E; Menees, Kelly B; Salas, Azucena; Aubrey Thompson, E; Tansey, Malú Gámez

RGS10 differentially modulates NFKB subunit transcription and inflammatory cytokine profiles in peritoneal macrophages

RGS10差异性地调节腹膜巨噬细胞中NFKB亚基的转录和炎症细胞因子谱

Posey, Janna E Jernigan; Dheeravath, Kruthika; Cole, Cassandra L; Neighbarger, Noelle K; Menees, Kelly B; Tansey, Malú Gámez

Iron mishandling in the brain and periphery in Parkinson's disease

帕金森病中大脑和外周的铁代谢异常

Bolen, MacKenzie L; Menees, Kelly B; Dupreez, Aidan C; Tansey, Malú Gámez

Correction: MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulation

更正:MHCII 减少不足以保护小鼠免受 α-突触核蛋白诱导的退行性变,帕金森病 HLA 位点表现出表观遗传调控。

Kline, Elizabeth M; Jernigan, Janna E; Scharer, Christopher D; Maurer, Jeffrey; Hicks, Sakeenah L; Herrick, Mary K; Wallings, Rebecca L; Kelly, Sean D; Chang, Jianjun; Menees, Kelly B; Manfredsson, Fredric P; McFarland, Nikolaus R; Boss, Jeremy M; Tansey, Malú Gámez; Joers, Valerie

Single-cell multiomics identifies both shared and unique features of immune dysfunction in Parkinson's disease and inflammatory bowel disease colon, plasma and stool

单细胞多组学分析揭示了帕金森病和炎症性肠病结肠、血浆和粪便中免疫功能障碍的共同特征和独特特征

Bolen, MacKenzie L; Buendia, Marc; Shi, Ji; Staley, Hannah; Kachergus, Jennifer M; Efron, Philip A; Park, Gwoncheol; Nagpal, Ravinder; Alvarez, Stephan D; Xue, Qing-Shan; McFarland, Nikolaus R; Zimmermann, Ellen M; Forsmark, Christopher E; Menees, Kelly B; Salas, Azucena; Thompson, E Aubrey; Tansey, Malú Gámez

Multiplex digital spatial profiling identifies subregion dependent targeted proteome changes across variants of dementia

多重数字空间分析可识别痴呆症不同变体中亚区域依赖性的靶向蛋白质组变化

Bolen, MacKenzie L; Menees, Kelly B; Gearing, Marla; Gong, Jingjing; Ren, Yuqi; Merchak, Andrea R; Murray, Melissa E; McEachin, Zachary T; Tansey, Malú Gámez

MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulation.

MHCII 减少不足以保护小鼠免受 α-突触核蛋白诱导的退化,帕金森病 HLA 位点表现出表观遗传调控

Kline Elizabeth M, Jernigan Janna E, Scharer Christopher D, Maurer Jeffrey, Hicks Sl Sakeenah, Herrick M Mary K, Wallings Rebecca L, Kelly Sean D, Chang Jianjun, Menees Kelly B, McFarland Nikolaus R, Boss Jeremy M, Tansey Malú Gámez, Joers Valerie

Thinking outside the brain: Gut microbiome influence on innate immunity within neurodegenerative disease

跳出大脑的局限:肠道微生物群对神经退行性疾病先天免疫的影响

Merchak, Andrea R; Bolen, MacKenzie L; Tansey, Malú Gámez; Menees, Kelly B

RGS10 mitigates high glucose-induced microglial inflammation via the reactive oxidative stress pathway and enhances synuclein clearance in microglia

RGS10通过活性氧化应激通路减轻高糖诱导的小胶质细胞炎症,并增强小胶质细胞中突触核蛋白的清除。

Chung, Jaegwon; Jernigan, Janna; Menees, Kelly B; Lee, Jae-Kyung

RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress.

RGS10 可减轻慢性炎症应激引起的全身免疫失调

Jernigan Janna E, Staley Hannah A, Baty Zachary, Bolen MacKenzie L, Gomes Beatriz Nuñes, Holt Jenny, Cole Cassandra L, Neighbarger Noelle K, Dheeravath Kruthika, Merchak Andrea R, Menees Kelly B, Coombes Stephen A, Tansey Malú Gámez