Meng Xiang-Yu相关文献与解析，生知库 | 链接生命科学的每一步

Integrated Multi-Omics Analysis and Cross-Model Validation Reveal Mitochondrial Signatures in Alzheimer's Disease

整合多组学分析和跨模型验证揭示阿尔茨海默病中的线粒体特征

期刊:CNS Neuroscience & Therapeutics

影响因子:5

doi:10.1111/cns.70634

Xu, Xuan; Fan, Sha-Sha; Li, Jiang; Wu, Hao; He, Junwen; He, Yang; Meng, Xiang-Yu; Shen, Yin

SysNatMed: rational natural medicine discovery by systems genetics

系统自然医学：通过系统遗传学进行理性自然药物发现

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2025.1496061

Ye, Chang-Qing; Leng, Jie; Jin, Meng-Yuan; Meng, Yuan-Dong; Zhao, Zi-Yi; Meng, Fan-Xing; Xu, Xuan; Fan, Sha-Sha; Luo, Hong-Bin; Meng, Xiang-Yu

发表日期：2025

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Deciphering novel mitochondrial signatures: multi-omics analysis uncovers cross-disease markers and oligodendrocyte pathways in Alzheimer's disease and glioblastoma

解读新型线粒体特征：多组学分析揭示阿尔茨海默病和胶质母细胞瘤中的跨疾病标志物和少突胶质细胞通路

期刊:Frontiers in Aging Neuroscience

影响因子:4.5

doi:10.3389/fnagi.2025.1536142

Xu, Xuan; Wang, Jiaqi; Chen, Tong; Wang, Shuaibin; Wang, Fei; He, Junwen; Meng, Xiang-Yu; Shen, Yin

Integrating causal human genetics and In vivo transcriptomics to uncover a shared lipid-centric architecture in metabolic and neurocognitive disease

整合因果人类遗传学和体内转录组学，揭示代谢和神经认知疾病中共同的以脂质为中心的结构

期刊:Frontiers in Molecular Biosciences

影响因子:4

doi:10.3389/fmolb.2025.1712198

Li, Yi; Ni, Zhu; Xia, Xiao-Yong; Cheng, Na; Bo, Yu; He, Junwen; He, Yang; Meng, Xiang-Yu; Wang, Xu; Xu, Xuan

Long non-coding RNA OSTM1-AS1 promotes renal cell carcinoma progression by sponging miR-491-5p and upregulating MMP-9

长链非编码RNA OSTM1-AS1通过海绵吸附miR-491-5p并上调MMP-9促进肾细胞癌进展。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-024-83154-4

Chen, Jun-Feng; Ye, Sha-Zhou; Wang, Ke-Jie; Meng, Xiang-Yu; Yang, Bin-Bin; Wu, Ke Rong; Ma, Qi

Sinularin induces autophagy-dependent cell death by activating ULK1 and enhancing FOXO3-ATG4A axis in prostate cancer cells.

Sinularin 通过激活 ULK1 和增强 FOXO3-ATG4A 轴诱导前列腺癌细胞发生自噬依赖性细胞死亡

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-00909-3

Meng Xiang-Yu, Li Yi, Yan Ze-Jun, Ye Sha-Zhou, Wang Ke-Jie, Chen Jun-Feng, Yu Rui, Ma Qi

Convergent and Divergent Mitochondrial Pathways as Causal Drivers and Therapeutic Targets in Neurological Disorders

线粒体趋同和发散通路作为神经系统疾病的致病驱动因素和治疗靶点

期刊:Current Issues in Molecular Biology

影响因子:3

doi:10.3390/cimb47080636

Du, Yanan; Fan, Sha-Sha; Wu, Hao; He, Junwen; He, Yang; Meng, Xiang-Yu; Xu, Xuan

Genetic Evidence Prioritizes Neurocognitive Decline as a Causal Driver of Sleep Disturbances: A Multi-Omics Analysis Identifying Causal Genes and Therapeutic Targets

遗传学证据表明神经认知衰退是睡眠障碍的主要致病因素：一项多组学分析识别了致病基因和治疗靶点

期刊:Current Issues in Molecular Biology

影响因子:3

doi:10.3390/cimb47110967

Du, Yanan; Xia, Xiao-Yong; Ni, Zhu; Fan, Sha-Sha; He, Junwen; He, Yang; Meng, Xiang-Yu; Wang, Xu; Xu, Xuan

神经科学

发表日期：2025

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GM-CSF(+) Th: a central player in autoimmunity

GM-CSF(+) Th：自身免疫中的核心角色

Research progress on circular RNA in the regulation of drug resistance in genitourinary cancers

环状RNA在泌尿生殖系统肿瘤耐药性调控中的研究进展

Integrated Multi-Omics Analysis and Cross-Model Validation Reveal Mitochondrial Signatures in Alzheimer's Disease

整合多组学分析和跨模型验证揭示阿尔茨海默病中的线粒体特征

SysNatMed: rational natural medicine discovery by systems genetics

系统自然医学：通过系统遗传学进行理性自然药物发现

Deciphering novel mitochondrial signatures: multi-omics analysis uncovers cross-disease markers and oligodendrocyte pathways in Alzheimer's disease and glioblastoma

解读新型线粒体特征：多组学分析揭示阿尔茨海默病和胶质母细胞瘤中的跨疾病标志物和少突胶质细胞通路

Integrating causal human genetics and In vivo transcriptomics to uncover a shared lipid-centric architecture in metabolic and neurocognitive disease

整合因果人类遗传学和体内转录组学，揭示代谢和神经认知疾病中共同的以脂质为中心的结构

Long non-coding RNA OSTM1-AS1 promotes renal cell carcinoma progression by sponging miR-491-5p and upregulating MMP-9

长链非编码RNA OSTM1-AS1通过海绵吸附miR-491-5p并上调MMP-9促进肾细胞癌进展。

Sinularin induces autophagy-dependent cell death by activating ULK1 and enhancing FOXO3-ATG4A axis in prostate cancer cells.

Sinularin 通过激活 ULK1 和增强 FOXO3-ATG4A 轴诱导前列腺癌细胞发生自噬依赖性细胞死亡

Convergent and Divergent Mitochondrial Pathways as Causal Drivers and Therapeutic Targets in Neurological Disorders

线粒体趋同和发散通路作为神经系统疾病的致病驱动因素和治疗靶点

Genetic Evidence Prioritizes Neurocognitive Decline as a Causal Driver of Sleep Disturbances: A Multi-Omics Analysis Identifying Causal Genes and Therapeutic Targets

遗传学证据表明神经认知衰退是睡眠障碍的主要致病因素：一项多组学分析识别了致病基因和治疗靶点