日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional Characterization of Pathway Inhibitors for the Ubiquitin-Proteasome System (UPS) as Tool Compounds for CRBN and VHL-Mediated Targeted Protein Degradation.

泛素-蛋白酶体系统 (UPS) 通路抑制剂的功能表征,作为 CRBN 和 VHL 介导的靶向蛋白质降解的工具化合物

Schwalm Martin P, Menge Amelie, Elson Lewis, Greco Francesco A, Robers Matthew B, Müller Susanne, Knapp Stefan

Repurposing of the RIPK1-Selective Benzo[1,4]oxazepin-4-one Scaffold for the Development of a Type III LIMK1/2 Inhibitor.

RIPK1 选择性苯并[1,4]氧氮杂环庚酮-4-酮骨架的再利用,用于开发 III 型 LIMK1/2 抑制剂

Mandel Sebastian, Hanke Thomas, Mathea Sebastian, Chatterjee Deep, Saraswati Hayuningbudi, Berger Benedict-Tilman, Schwalm Martin Peter, Yamamoto Satoshi, Tawada Michiko, Takagi Terufumi, Ahmed Mahmood, Röhm Sandra, Corrionero Ana, Alfonso Patricia, Baena Maria, Elson Lewis, Menge Amelie, Krämer Andreas, Pereira Raquel, Müller Susanne, Krause Daniela S, Knapp Stefan

A data science roadmap for open science organizations engaged in early-stage drug discovery

面向从事早期药物研发的开放科学组织的数据科学路线图

Edfeldt, Kristina; Edwards, Aled M; Engkvist, Ola; Günther, Judith; Hartley, Matthew; Hulcoop, David G; Leach, Andrew R; Marsden, Brian D; Menge, Amelie; Misquitta, Leonie; Müller, Susanne; Owen, Dafydd R; Schütt, Kristof T; Skelton, Nicholas; Steffen, Andreas; Tropsha, Alexander; Vernet, Erik; Wang, Yanli; Wellnitz, James; Willson, Timothy M; Clevert, Djork-Arné; Haibe-Kains, Benjamin; Schiavone, Lovisa Holmberg; Schapira, Matthieu

Unlocking the potential: unveiling tyrphostins with Michael-reactive cyanoacrylate motif as promising inhibitors of human 5-lipoxygenase

释放潜能:揭示具有迈克尔反应性氰基丙烯酸酯基序的酪氨酸激酶抑制剂作为人类5-脂氧合酶的潜在抑制剂

Molitor, Maximilian; Menge, Amelie; Mandel, Sebastian; George, Sven; Müller, Susanne; Knapp, Stefan; Hofmann, Bettina; Steinhilber, Dieter; Häfner, Ann-Kathrin