日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Opposing diet, microbiome, and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host

饮食、微生物群和代谢机制相互拮抗,共同调节遗传易感宿主的炎症性肠病。

Gabriel Vasconcelos Pereira ,Marie Boudaud ,Mathis Wolter ,Celeste Alexander ,Alessandro De Sciscio ,Erica T Grant ,Bruno Caetano Trindade ,Nicholas A Pudlo ,Shaleni Singh ,Austin Campbell ,Mengrou Shan ,Li Zhang ,Qinnan Yang ,Stéphanie Willieme ,Kwi Kim ,Trisha Denike-Duval ,Jaime Fuentes ,André Bleich ,Thomas M Schmidt ,Lucy Kennedy ,Costas A Lyssiotis ,Grace Y Chen ,Kathryn A Eaton ,Mahesh S Desai ,Eric C Martens

Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma

针对弥漫性中线胶质瘤分化状态依赖性代谢脆弱性的治疗靶向治疗

Nneka E Mbah ,Amy L Myers ,Peter Sajjakulnukit ,Chan Chung ,Joyce K Thompson ,Hanna S Hong ,Heather Giza ,Derek Dang ,Zeribe C Nwosu ,Mengrou Shan ,Stefan R Sweha ,Daniella D Maydan ,Brandon Chen ,Li Zhang ,Brian Magnuson ,Zirui Zhu ,Megan Radyk ,Brooke Lavoie ,Viveka Nand Yadav ,Imhoi Koo ,Andrew D Patterson ,Daniel R Wahl ,Luigi Franchi ,Sameer Agnihotri ,Carl J Koschmann ,Sriram Venneti ,Costas A Lyssiotis

Quiescence enables unrestricted cell fate in naive embryonic stem cells

静止状态使原始胚胎干细胞能够不受限制地决定其细胞命运。

Le Tran Phuc Khoa ,Wentao Yang ,Mengrou Shan ,Li Zhang ,Fengbiao Mao ,Bo Zhou ,Qiang Li ,Rebecca Malcore ,Clair Harris ,Lili Zhao ,Rajesh C Rao ,Shigeki Iwase ,Sundeep Kalantry ,Stephanie L Bielas ,Costas A Lyssiotis ,Yali Dou

Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions

苹果酸酶 1 敲除没有有害表型,并且在标准实验室条件下在雄性生殖系中占优势

Jonathan M Alektiar, Mengrou Shan, Megan D Radyk, Li Zhang, Christopher J Halbrook, Lin Lin, Carlos Espinoza, Ivan F Mier, Brooke L Lavoie, Lucie Salvatore, Marina Pasca di Magliano, Lewis C Cantley, Jacob L Mueller, Costas A Lyssiotis

Feasibility of a dietary intervention to modify gut microbial metabolism in patients with hematopoietic stem cell transplantation

饮食干预改变造血干细胞移植患者肠道微生物代谢的可行性

Mary M Riwes, Jonathan L Golob, John Magenau, Mengrou Shan, Gregory Dick, Thomas Braun, Thomas M Schmidt, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Darren King, Sung Choi, Gregory Yanik, Marcus Geer, Ethan Hillman, Costas A Lyssiotis, Muneesh Tewari, Pavan Reddy

Unravelling specific diet and gut microbial contributions to inflammatory bowel disease

揭示特定饮食和肠道微生物对炎症性肠病的影响

Gabriel Vasconcelos Pereira, Marie Boudaud, Mathis Wolter, Celeste Alexander, Alessandro De Sciscio, Erica T Grant, Bruno Caetano Trindade, Nicholas A Pudlo, Shaleni Singh, Austin Campbell, Mengrou Shan, Li Zhang, Stéphanie Willieme, Kwi Kim, Trisha Denike-Duval, André Bleich, Thomas M Schmidt, Lucy

OXPHOS promotes apoptotic resistance and cellular persistence in TH17 cells in the periphery and tumor microenvironment

OXPHOS 促进外周和肿瘤微环境中 TH17 细胞的凋亡抗性和细胞持久性

Hanna S Hong, Nneka E Mbah, Mengrou Shan, Kristen Loesel, Lin Lin, Peter Sajjakulnukit, Luis O Correa, Anthony Andren, Jason Lin, Atsushi Hayashi, Brian Magnuson, Judy Chen, Zhaoheng Li, Yuying Xie, Li Zhang, Daniel R Goldstein, Shannon A Carty, Yu Leo Lei, Anthony W Opipari, Rafael J Argüello, Ilon

Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection

肠道菌群衍生的代谢产物可预防SARS-CoV-2感染

Julia A Brown ,Katherine Z Sanidad ,Serena Lucotti ,Carolin M Lieber ,Robert M Cox ,Aparna Ananthanarayanan ,Srijani Basu ,Justin Chen ,Mengrou Shan ,Mohammed Amir ,Fabian Schmidt ,Yiska Weisblum ,Michele Cioffi ,Tingting Li ,Florencia Madorsky Rowdo ,M Laura Martin ,Chun-Jun Guo ,Costas Lyssiotis ,Brian T Layden ,Andrew J Dannenberg ,Paul D Bieniasz ,Benhur Lee ,Naohiro Inohara ,Irina Matei ,Richard K Plemper ,Melody Y Zeng

Human Norovirus Triggers Primary B Cell Immune Activation In Vitro

人诺如病毒在体外触发原代B细胞免疫活化

Carmen Mirabelli ,Melissa K Jones ,Vivienne L Young ,Abimbola O Kolawole ,Irene Owusu ,Mengrou Shan ,Basel Abuaita ,Holly Turula ,Jose G Trevino ,Irina Grigorova ,Steven K Lundy ,Costas A Lyssiotis ,Vernon K Ward ,Stephanie M Karst ,Christiane E Wobus

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

GOT1抑制剂通过铁死亡促进胰腺癌细胞死亡

Daniel M Kremer ,Barbara S Nelson ,Lin Lin ,Emily L Yarosz ,Christopher J Halbrook ,Samuel A Kerk ,Peter Sajjakulnukit ,Amy Myers ,Galloway Thurston ,Sean W Hou ,Eileen S Carpenter ,Anthony C Andren ,Zeribe C Nwosu ,Nicholas Cusmano ,Stephanie Wisner ,Nneka E Mbah ,Mengrou Shan ,Nupur K Das ,Brian Magnuson ,Andrew C Little ,Milan R Savani ,Johanna Ramos ,Tina Gao ,Stephen A Sastra ,Carmine F Palermo ,Michael A Badgley ,Li Zhang ,John M Asara ,Samuel K McBrayer ,Marina Pasca di Magliano ,Howard C Crawford ,Yatrik M Shah ,Kenneth P Olive ,Costas A Lyssiotis