日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma

异常的MYCN表达驱动EZH2作为转录激活因子在周围T细胞淋巴瘤中发生致癌劫持

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2022016428
Vanden Bempt, Marlies; Debackere, Koen; Demeyer, Sofie; Van Thillo, Quentin; Meeuws, Nienke; Prieto, Cristina; Provost, Sarah; Mentens, Nicole; Jacobs, Kris; Gielen, Olga; Nittner, David; Ogawa, Seishi; Kataoka, Keisuke; Graux, Carlos; Tousseyn, Thomas; Cools, Jan; Dierickx, Daan
T细胞
T细胞
MYC
EZH2
免疫/内分泌
肿瘤
淋巴瘤
细胞生物学
肿瘤免疫
发表日期：2022
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Oncogenic Cooperation Between IL7R-JAK-STAT Pathway Mutations

IL7R-JAK-STAT通路突变之间的致癌协同作用

期刊:Hemasphere
影响因子:14.6
doi:10.1097/HS9.0000000000000637
Lodewijckx, Inge; Mentens, Nicole; Jacobs, Kris; Cools, Jan
肿瘤
肿瘤免疫
JAK/STAT
信号转导
IL7R
发表日期：2021
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Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.

Suz12 失活与 JAK3 突变信号传导协同作用，导致 T 细胞急性淋巴细胞白血病的发生

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2019000015
Broux Michael, Prieto Cristina, Demeyer Sofie, Vanden Bempt Marlies, Alberti-Servera Llucia, Lodewijckx Inge, Vandepoel Roel, Mentens Nicole, Gielen Olga, Jacobs Kris, Geerdens Ellen, Vicente Carmen, de Bock Charles E, Cools Jan
信号转导
细胞生物学
白血病
发表日期：2019
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EML1-ABL1 Is Activated by Coiled-Coil-Mediated Oligomerization and Induces T-Cell Acute Lymphoblastic Leukemia or Myeloproliferative Disease in a Mouse Bone Marrow Transplant Model

EML1-ABL1通过卷曲螺旋介导的寡聚化激活，并在小鼠骨髓移植模型中诱导T细胞急性淋巴细胞白血病或骨髓增生性疾病。

期刊:Hemasphere
影响因子:14.6
doi:10.1097/HS9.0000000000000032
Vanden Bempt, Marlies; Mentens, Nicole; Vandenberghe, Peter; Cools, Jan; De Keersmaecker, Kim
T细胞
ABL1
白血病
T细胞
细胞生物学
Mouse
免疫/内分泌
发表日期：2018
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Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene

伴有RNF213、ATIC和TPM3-ALK融合变异的间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤的特征是重排的ALK基因拷贝数增加。

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2016.146571
van der Krogt, Jo-Anne; Bempt, Marlies Vanden; Ferreiro, Julio Finalet; Mentens, Nicole; Jacobs, Kris; Pluys, Ursula; Doms, Kathleen; Geerdens, Ellen; Uyttebroeck, Anne; Pierre, Pascal; Michaux, Lucienne; Devos, Timothy; Vandenberghe, Peter; Tousseyn, Thomas; Cools, Jan; Wlodarska, Iwona
信号转导
细胞生物学
ALK
淋巴瘤
发表日期：2017
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Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

T细胞急性淋巴细胞白血病中蛋白酪氨酸磷酸酶基因PTPN2的缺失

期刊:Nature Genetics
影响因子:29
doi:10.1038/ng.587
Kleppe, Maria; Lahortiga, Idoya; El Chaar, Tiama; De Keersmaecker, Kim; Mentens, Nicole; Graux, Carlos; Van Roosbroeck, Katrien; Ferrando, Adolfo A; Langerak, Anton W; Meijerink, Jules P P; Sigaux, François; Haferlach, Torsten; Wlodarska, Iwona; Vandenberghe, Peter; Soulier, Jean; Cools, Jan
T细胞
白血病
T细胞
细胞生物学
免疫/内分泌
发表日期：2010
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Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant

索拉非尼是FIP1L1-PDGFRα及其伊马替尼耐药突变体T674I的强效抑制剂。

期刊:Blood
影响因子:23.1
doi:10.1182/blood-2006-02-004457
Lierman, Els; Folens, Cedric; Stover, Elizabeth H; Mentens, Nicole; Van Miegroet, Helen; Scheers, Werner; Boogaerts, Marc; Vandenberghe, Peter; Marynen, Peter; Cools, Jan
发表日期：2006
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Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent

FIP1L1-PDGFRα复合物的激活需要破坏PDGFRα的近膜结构域，且与FIP1L1无关。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0601192103
Stover, Elizabeth H; Chen, Jing; Folens, Cedric; Lee, Benjamin H; Mentens, Nicole; Marynen, Peter; Williams, Ifor R; Gilliland, D Gary; Cools, Jan
发表日期：2006
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