日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Expanding the Molecular and Pathologic Spectrum of HSPB8 Myopathy and Distal Motor Neuropathy

拓展 HSPB8 肌病和远端运动神经病的分子和病理谱

Putko, Brendan Nicholas; Sorenson, Eric J; Cui, Gaofeng; Liewluck, Teerin; Niu, Zhiyv; Litchy, William J; Mer, Georges; Milone, Margherita

Identification of a conserved α-helical domain at the N terminus of human DNA methyltransferase 1

人类DNA甲基转移酶1 N端保守α螺旋结构域的鉴定

Hu, Qi; Botuyan, Maria Victoria; Mer, Georges

Hidden tricks in MATH: Hypermorphic mutations in SPOP tumor suppressor explained by cryo-EM

数学中的隐藏技巧:冷冻电镜揭示SPOP肿瘤抑制基因超形态突变的奥秘

Orme, Jacob J; Mer, Georges; Huang, Haojie

An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

小分子拮抗剂和蛋白质工程揭示了53BP1的自身抑制状态

Cui, Gaofeng; Botuyan, Maria Victoria; Drané, Pascal; Hu, Qi; Bragantini, Benoît; Thompson, James R; Schuller, David J; Detappe, Alexandre; Perfetti, Michael T; James, Lindsey I; Frye, Stephen V; Chowdhury, Dipanjan; Mer, Georges

A chemical strategy to study transient states in substrate ubiquitylation by cryo-EM

利用冷冻电镜研究底物泛素化瞬态的化学策略

Hu, Qi; Botuyan, Maria Victoria; Mer, Georges

Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes.

人类 FACT 亚基协同作用,催化核小体的解体和重组

McCauley Micah J, Morse Michael, Becker Nicole, Hu Qi, Botuyan Maria Victoria, Navarrete Emily, Huo Ran, Muthurajan Uma M, Rouzina Ioulia, Luger Karolin, Mer Georges, Maher L James 3rd, Williams Mark C

Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation

BRCA1-BARD1核小体识别和泛素化的机制

Qi Hu #, Maria Victoria Botuyan #, Debiao Zhao #, Gaofeng Cui, Elie Mer, Georges Mer

Cryo-EM reveals conformational flexibility in apo DNA polymerase ζ

冷冻电镜揭示了脱辅基DNA聚合酶ζ的构象灵活性

Du Truong, Chloe; Craig, Theodore A; Cui, Gaofeng; Botuyan, Maria Victoria; Serkasevich, Rachel A; Chan, Ka-Yi; Mer, Georges; Chiu, Po-Lin; Kumar, Rajiv

Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin

突变体组装因子 REV1 与泛素相互作用的结构基础

Cui, Gaofeng; Botuyan, Maria Victoria; Mer, Georges

Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18

RNF168/169 和 RAD18 对泛素-核小体识别和 53BP1 染色质募集的调控机制

Hu, Qi; Botuyan, Maria Victoria; Cui, Gaofeng; Zhao, Debiao; Mer, Georges