日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Oncogenomic profiling in infant-toddler T-ALL identifies NKX2 family genes as drivers linked to favorable outcomes

婴幼儿T细胞急性淋巴细胞白血病(T-ALL)的肿瘤基因组分析发现,NKX2家族基因是与良好预后相关的驱动因素。

Delafoy, Manon; Balducci, Estelle; Simonin, Mathieu; Pinton, Antoine; Charbonnier, Guillaume; Courtois, Lucien; Lhermitte, Ludovic; Gillet, Camille; Féroul, Mélanie; Touzart, Aurore; Cieslak, Agata; Smith, Charlotte; Courgeon, Marianne; Wiber, Margaux; Mercher, Thomas; Latour, Sylvain; Arnoux, Isabelle; Saultier, Paul; Rohrlich, Pierre-Simon; Bodet, Damien; Grardel, Nathalie; Lubnau, Marion; Pellier, Isabelle; Thouvenin, Sandrine; Garnier, Nathalie; Pastoret, Cédric; Brethon, Benoit; Petit, Arnaud; Macintyre, Elizabeth; Baruchel, André; Asnafi, Vahid

From hypoxia single-cell gene signatures to HIF targeting of AML leukemic stem cells

从缺氧单细胞基因特征到靶向急性髓系白血病干细胞的HIF

Mercher, Thomas; Schwaller, Juerg

Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia

DYRK1A抑制剂在唐氏综合征急性淋巴细胞白血病新型模型中的疗效

Carey-Smith, Shannon L; Simad, Maryam H; Panchal, Kunjal; Aya-Bonilla, Carlos; Smolders, Hannah; Lin, Sang; Armitage, Jesse D; Nguyen, Vivien T; Bentley, Kathryn; Ford, Jette; Singh, Sajla; Oommen, Joyce; Laurent, Anouchka P; Mercher, Thomas; Crispino, John D; Montgomery, Andrew P; Kassiou, Michael; Besson, Thierry; Deau, Emmanuel; Meijer, Laurent; Cheung, Laurence C; Kotecha, Rishi S; Malinge, Sébastien

The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53

NFIA-ETO2融合蛋白阻断红系细胞成熟,并与突变型TP53协同诱导纯红系白血病。

Piqué-Borràs, Maria-Riera; Jevtic, Zivojin; Bagger, Frederik Otzen; Seguin, Jonathan; Sivalingam, Rathick; Bezerra, Matheus Filgueira; Louwagie, Amber; Juge, Sabine; Nellas, Ioannis; Ivanek, Robert; Tzankov, Alexandar; Moll, Ute M; Cantillo, Oriano; Schulz-Heddergott, Ramona; Fagnan, Alexandre; Mercher, Thomas; Schwaller, Juerg

High caspase 3 and vulnerability to dual BCL2 family inhibition define ETO2::GLIS2 pediatric leukemia

高水平的 caspase 3 和对双重 BCL2 家族抑制剂的敏感性是 ETO2::GLIS2 儿童白血病的特征。

Aid, Zakia; Robert, Elie; Lopez, Cécile K; Bourgoin, Maxence; Boudia, Fabien; Le Mene, Melchior; Riviere, Julie; Baille, Marie; Benbarche, Salima; Renou, Laurent; Fagnan, Alexandre; Thirant, Cécile; Federici, Laetitia; Touchard, Laure; Lecluse, Yann; Jetten, Anton; Geoerger, Birgit; Lapillonne, Hélène; Solary, Eric; Gaudry, Muriel; Meshinchi, Soheil; Pflumio, Françoise; Auberger, Patrick; Lobry, Camille; Petit, Arnaud; Jacquel, Arnaud; Mercher, Thomas

ETS Fight Club on Microsatellite Enhancers

ETS搏击俱乐部关于微卫星增强器

Mercher, Thomas

A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors

癌症精准医疗试验 MAPPYACTS 中用于治疗复发和难治性肿瘤的儿科患者来源异种移植模型生物样本库

Marques Da Costa, Maria Eugénia; Zaidi, Sakina; Scoazec, Jean-Yves; Droit, Robin; Lim, Wan Ching; Marchais, Antonin; Salmon, Jerome; Cherkaoui, Sarah; Morscher, Raphael J; Laurent, Anouchka; Malinge, Sébastien; Mercher, Thomas; Tabone-Eglinger, Séverine; Goddard, Isabelle; Pflumio, Francoise; Calvo, Julien; Redini, Francoise; Entz-Werlé, Natacha; Soriano, Aroa; Villanueva, Alberto; Cairo, Stefano; Chastagner, Pascal; Moro, Massimo; Owens, Cormac; Casanova, Michela; Hladun-Alvaro, Raquel; Berlanga, Pablo; Daudigeos-Dubus, Estelle; Dessen, Philippe; Zitvogel, Laurence; Lacroix, Ludovic; Pierron, Gaelle; Delattre, Olivier; Schleiermacher, Gudrun; Surdez, Didier; Geoerger, Birgit

De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

从头生成的NPM-ALK融合基因重现了ALK阳性间变性大细胞淋巴瘤(ALCL)发病机制的多效性表型,并揭示了ROR2受体是肿瘤细胞的靶点。

Loélia Babin # ,Alice Darchen # ,Elie Robert ,Zakia Aid ,Rosalie Borry ,Claire Soudais ,Marion Piganeau ,Anne De Cian ,Carine Giovannangeli ,Olivia Bawa ,Charlotte Rigaud ,Jean-Yves Scoazec ,Lucile Couronné ,Layla Veleanu ,Agata Cieslak ,Vahid Asnafi ,David Sibon ,Laurence Lamant ,Fabienne Meggetto ,Thomas Mercher ,Erika Brunet

Molecular Landscapes and Models of Acute Erythroleukemia

急性红白血病的分子图谱和模型

Fagnan, Alexandre; Piqué-Borràs, Maria-Riera; Tauchmann, Samantha; Mercher, Thomas; Schwaller, Juerg

JAM-C/Jam-C Expression Is Primarily Expressed in Mouse Hematopoietic Stem Cells

JAM-C/Jam-C表达主要在小鼠造血干细胞中表达

Henry, Elia; Barroca, Vilma; Lopez, Cécile K; Aurrand-Lions, Michel; Lewandowski, Daniel; Mercher, Thomas; Arcangeli, Marie-Laure