日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Selective SIK2/SIK3 inhibition reprograms pro- and antiinflammatory pathways in myeloid cells, improving autoimmune disease outcomes

选择性抑制SIK2/SIK3可重编程髓系细胞中的促炎和抗炎通路，从而改善自身免疫性疾病的预后。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.171776
De Vos, Steve; Desroy, Nicolas; Bellaire, Susan J; Fernandes, Anna Pereira; Lavazais, Stéphanie; Merciris, Didier; Delachaume, Carole; Robin-Jagerschmidt, Catherine; Cosson, Adrien; Lazaryan, Angela; Van Osselaer, Nancy; Amantini, David; Peixoto, Christophe; Colli, Maikel L; Van Eeckhoutte, Thomas; Hakonen, Tiina; Constant, Magali; Garcia-Hernandez, Alberto; Barron, Rahul; D'Haens, Geert; Böcher, Wulf O
信号转导
自身免疫性疾病
免疫/内分泌
细胞生物学
发表日期：2026
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Tissular chromatin-state cartography based on double-barcoded DNA arrays that capture unloaded PA-Tn5 transposase.

基于捕获未加载的 PA-Tn5 转座酶的双条形码 DNA 阵列的组织染色质状态图谱

期刊:Genome Research
影响因子:5.5
doi:10.1101/gr.280305.124
Mendoza-Ferri Maria Grazia, Lozachmeur Gwendoline, Duvina Maximilien, Perret Laetitia, Merciris Didier, Gigout Anne, Mendoza-Parra Marco Antonio
免疫/内分泌
发表日期：2025
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Discovery of Clinical Candidate GLPG3970: A Potent and Selective Dual SIK2/SIK3 Inhibitor for the Treatment of Autoimmune and Inflammatory Diseases

发现临床候选药物 GLPG3970：一种用于治疗自身免疫和炎症疾病的强效选择性双重 SIK2/SIK3 抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c02246
Christophe Peixoto, Agnes Joncour, Taouès Temal-Laib, Amynata Tirera, Aurélie Dos Santos, Hélène Jary, Denis Bucher, Wendy Laenen, Anna Pereira Fernandes, Stephanie Lavazais, Carole Delachaume, Didier Merciris, Corinne Saccomani, Michael Drennan, Miriam López-Ramos, Emanuelle Wakselman, Sonia Dupont
免疫
发表日期：2024
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Biological and Chemical Characterization of Musa paradisiaca Leachate

芭蕉浸出液的生物学和化学特性

期刊:Biology-Basel
影响因子:3.5
doi:10.3390/biology12101326
Boulogne, Isabelle; Petit, Philippe; Desfontaines, Lucienne; Durambur, Gaëlle; Deborde, Catherine; Mirande-Ney, Cathleen; Arnaudin, Quentin; Plasson, Carole; Grivotte, Julie; Chamot, Christophe; Bernard, Sophie; Loranger-Merciris, Gladys
发表日期：2023
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Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species

利用活性氧修饰的 II 型胶原蛋白特异性抗体早期检测大鼠骨关节炎

期刊:Arthritis Research & Therapy
影响因子:4.4
doi:10.1186/s13075-021-02502-1
Anne Gigout, Donata Harazin, Louise M Topping, Didier Merciris, Sven Lindemann, Christian Brenneis, Ahuva Nissim
免疫
关节炎
Rat
发表日期：2021
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Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization

在小鼠后肢固定模型中对选择性雄激素受体调节剂GLPG0492进行表征

期刊:BMC Musculoskeletal Disorders
影响因子:2.4
doi:10.1186/1471-2474-15-291
Blanqué, Roland; Lepescheux, Liên; Auberval, Marielle; Minet, Dominique; Merciris, Didier; Cottereaux, Céline; Clément-Lacroix, Philippe; Delerive, Philippe; Namour, Florence
信号转导
免疫/内分泌
发表日期：2014
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