Mercurio Arthur M相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth.

将靶向 IRS2 的白蛋白结合 siRNA 治疗性递送至多种细胞类型可减少乳腺肿瘤的生长。

期刊:Molecular Therapy

影响因子:12

doi:10.1016/j.ymthe.2026.01.033

Tocheny Claire E, Buchwald Julianna E, Dahlke Christopher D, Fakih Hassan H, Morgan Jennifer S, Summers Ashley, Silva Christi A, Jackson Samuel O, Lee Ji-Sun, Card Michael-Anthony, Echeverria Dimas, Peterson Cornelia, Mercurio Arthur M, Khvorova Anastasia, Shaw Leslie M

细胞生物学

发表日期：2026

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Folate Receptor α Contributes to Radiation Resistance in Neuroendocrine Prostate Cancer by Regulating Redox Homeostasis

叶酸受体α通过调节氧化还原稳态促进神经内分泌前列腺癌的放射抗性

doi:10.64898/2026.03.26.714502

Goel, Hira Lal; Wang, Tao; Dimitrov, Boris S; Kumar, Ayush; Silva, Christi A; FitzGerald, Thomas J; Mercurio, Arthur M

发表日期：2026

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Targeting BRCA1-deficient PARP inhibitor-resistant cells with nickases reveals nick resection as a cancer vulnerability.

利用切口酶靶向 BRCA1 缺陷的 PARP 抑制剂耐药细胞，揭示切口切除是癌症的弱点

期刊:Nature Cancer

影响因子:28.5

doi:10.1038/s43018-024-00902-1

Whalen Jenna M, Earley Jillian, Wisniewski Christi, Mercurio Arthur M, Cantor Sharon B

细胞生物学

发表日期：2025

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MYC and p53 Alterations Cooperate through VEGF Signaling to Repress Cytotoxic T Cell and Immunotherapy Responses in Prostate Cancer.

MYC 和 p53 的改变通过 VEGF 信号传导协同作用，抑制前列腺癌中的细胞毒性 T 细胞和免疫疗法反应

期刊:Cancer Research

影响因子:16.6

doi:10.1158/0008-5472.CAN-25-2532

Murphy Katherine C, DeMarco Kelly D, Zhou Lin, Peura Jessica, Giwa Hadiya K, Lopez-Diaz Yvette, Ho Yu-Jui, Li Junhui, Bai Shi, Simin Karl, Zhu Lihua J, Pitarresi Jason R, Mercurio Arthur M, Ruscetti Marcus

细胞生物学

发表日期：2025

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Resistance to radiation enhances metastasis by altering RNA metabolism

放射抗性通过改变RNA代谢增强转移。

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.adx3050

Kumar, Ayush; Kishimoto, Kensei; Goel, Hira L; Silva, Christi A; Li, Rui; Pacheco, Brendan; Zhu, Lihua J; Flavahan, William A; Mercurio, Arthur M

发表日期：2025

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GATA3 promotes ferroptosis resistance by repressing integrin Î²1 signaling.

GATA3 通过抑制整合素 β1 信号传导来促进铁死亡抵抗

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2427304122

Karner Emmet R, Wang Mengdie, Goel Hira Lal, Mercurio Arthur M

发表日期：2025

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Inducing ferroptosis to impede metastasis by inhibiting the calcium channel TRPC6.

通过抑制钙通道 TRPC6 诱导铁死亡以阻止转移。

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2025.116543

Dimitrov Boris S, Mukhopadhyay Dimpi, Goel Hira Lal, Karner Emmet R, Silva Christi A, Kumar Ayush, Peterson Cornelia, Wang Mengdie, Mercurio Arthur M

发表日期：2025

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Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth

将靶向IRS2的白蛋白结合siRNA治疗性递送至多种细胞类型可减少乳腺肿瘤的生长

doi:10.1101/2025.07.29.667434

Tocheny, Claire E; Buchwald, Julianna E; Dahlke, Christopher D; Fakih, Hassan H; Morgan, Jennifer S; Summers, Ashley; Wisniewski, Christi A; Jackson, Samuel O; Lee, Ji-Sun; Card, Michael-Anthony; Echeverria, Dimas; Peterson, Cornelia; Mercurio, Arthur M; Khvorova, Anastasia; Shaw, Leslie M

细胞生物学

发表日期：2025

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Resistance to Radiation Enhances Metastasis by Altering RNA Metabolism.

放射抗性通过改变RNA代谢增强转移

doi:10.1101/2025.02.19.638943

Kumar Ayush, Kishimoto Kensei, Goel Hira Lal, Wisniewski Christi A, Li Rui, Pacheco Brendan, Zhu Lihua Julie, Flavahan William A, Mercurio Arthur M

发表日期：2025

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Prevalence of BRAF V600 in primary gliomas: a systematic review

BRAF V600在原发性胶质瘤中的患病率：系统评价

期刊:EMBO Molecular Medicine

影响因子:8.3

doi:10.1002/emmm.201202078

Goel, Hira Lal; Pursell, Bryan; Chang, Cheng; Shaw, Leslie M; Mao, Junhao; Simin, Karl; Kumar, Prashant; Vander Kooi, Craig W; Shultz, Leonard D; Greiner, Dale L; Norum, Jens Henrik; Toftgard, Rune; Kuperwasser, Charlotte; Mercurio, Arthur M; Andrews, Lily; Thornton, Zak; Saincher, Samir; Dawson, Sarah; Cheng, Vincent; Higgins, Julian; McAleenan, Alexandra; Kurian, Kathreena

发表日期：2021

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