日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cells

抑制性共受体CTLA-4的缺失可增强并激活嵌合抗原受体T细胞。

Sangya Agarwal ,M Angela Aznar ,Andrew J Rech ,Charly R Good ,Shunichiro Kuramitsu ,Tong Da ,Mercy Gohil ,Linhui Chen ,Seok-Jae Albert Hong ,Pranali Ravikumar ,Austin K Rennels ,January Salas-Mckee ,Weimin Kong ,Marco Ruella ,Megan M Davis ,Gabriela Plesa ,Joseph A Fraietta ,David L Porter ,Regina M Young ,Carl H June

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

慢性淋巴细胞白血病对 CD19 嵌合抗原受体 (CAR) T 细胞疗法的疗效和耐药性的决定因素

Joseph A Fraietta, Simon F Lacey #, Elena J Orlando #, Iulian Pruteanu-Malinici, Mercy Gohil, Stefan Lundh, Alina C Boesteanu, Yan Wang, Roddy S O'Connor, Wei-Ting Hwang, Edward Pequignot, David E Ambrose, Changfeng Zhang, Nicholas Wilcox, Felipe Bedoya, Corin Dorfmeier, Fang Chen, Lifeng Tian, Hari

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

TET2 的破坏可增强 CD19 靶向 T 细胞的治疗效果

Joseph A Fraietta, Christopher L Nobles, Morgan A Sammons, Stefan Lundh, Shannon A Carty, Tyler J Reich, Alexandria P Cogdill, Jennifer J D Morrissette, Jamie E DeNizio, Shantan Reddy, Young Hwang, Mercy Gohil, Irina Kulikovskaya, Farzana Nazimuddin, Minnal Gupta, Fang Chen, John K Everett, Katherin

mTORC2 regulates multiple aspects of NKT-cell development and function

mTORC2 调节 NKT 细胞发育和功能的多个方面

Tammarah Sklarz, Peng Guan, Mercy Gohil, Renee M Cotton, Moyar Q Ge, Angela Haczku, Rupali Das, Martha S Jordan

Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis

软组织肉瘤中 Hippo 通路失调促进 FOXM1 表达和肿瘤发生

T S Karin Eisinger-Mathason, Vera Mucaj, Kevin M Biju, Michael S Nakazawa, Mercy Gohil, Timothy P Cash, Sam S Yoon, Nicolas Skuli, Kyung Min Park, Sharon Gerecht, M Celeste Simon

Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways

天然和诱导型TH17细胞受Akt和mTOR通路调控的方式不同。

Jiyeon S Kim ,Tammarah Sklarz, Lauren B Banks, Mercy Gohil, Adam T Waickman, Nicolas Skuli, Bryan L Krock, Chong T Luo, Weihong Hu, Kristin N Pollizzi, Ming O Li, Jeffrey C Rathmell, Morris J Birnbaum, Jonathan D Powell, Martha S Jordan, Gary A Koretzky

The SLP-76 Src homology 2 domain is required for T cell development and activation

SLP-76 Src 同源性 2 结构域是 T 细胞发育和激活所必需的

Jeremy C Burns, Evann Corbo, Janine Degen, Mercy Gohil, Christine Anterasian, Burkart Schraven, Gary A Koretzky, Stefanie Kliche, Martha S Jordan