日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Plant fucosyltransferase FUT11 distorts the sugar acceptor to catalyze via a transient oxocarbenium intermediate mechanism

植物岩藻糖基转移酶FUT11通过瞬态氧碳正离子中间体机制，使糖受体发生畸变，从而催化反应。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68786-6
Taleb, Víctor; Sanz-Martínez, Ignacio; Serna, Sonia; Bort-Griñó, María; Narimatsu, Yoshiki; Furukawa, Sanae; Reichardt, Niels C; Clausen, Henrik; Merino, Pedro; Hurtado-Guerrero, Ramon
信号转导
发表日期：2026
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FUT8 Catalysis Involves GDP-Fucose-Induced Loop Activation Promoting a Reaction at the S(N)1‑S(N)2 Frontier

FUT8 催化作用涉及 GDP-岩藻糖诱导的环活化，从而促进 S(N)1-S(N)2 前沿的反应。

期刊:ACS Catalysis
影响因子:13.1
doi:10.1021/acscatal.5c07826
Sanz-Martínez, Ignacio; Tejero, Tomás; Hurtado-Guerrero, Ramón; Merino, Pedro
发表日期：2026
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Synthesis of Polyhydroxylated Pyrrolidinyl Analogs of Sugar Nucleotides. Experimental and Computational Studies on Their Interactions With GalNAC-T's

多羟基吡咯烷基糖核苷酸类似物的合成。其与GalNAC-T相互作用的实验和计算研究

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.202500955
Merino, Pedro; Juste, Veronica; Montesa, Alejandro; Pereira, Sandra; Orta, Sara; Pedrón, Manuel; Jiménez, Ana I; Martín-Santamaría, Sonsoles; Hurtado-Guerrero, Ramón; Delso, Ignacio; Tejero, Tomás
发表日期：2026
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Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins

微生物结合模块采用复杂的簇状糖类斑块，选择性地粘附于粘蛋白。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63756-w
Jaroentomeechai, Thapakorn; Veloz, Billy; Soares, Cátia O; Goerdeler, Felix; Grosso, Ana Sofia; Büll, Christian; Miller, Rebecca L; Furukawa, Sanae; Ginés-Alcober, Irene; Taleb, Víctor; Merino, Pedro; Ghirardello, Mattia; Compañón, Ismael; Coelho, Helena; Dias, Jorge S; Vincentelli, Renaud; Henrissat, Bernard; Joshi, Hiren; Clausen, Henrik; Corzana, Francisco; Marcelo, Filipa; Hurtado-Guerrero, Ramon; Narimatsu, Yoshiki
微生物学
发表日期：2025
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Structure, function, and implications of fucosyltransferases in health and disease

岩藻糖基转移酶的结构、功能及其在健康和疾病中的作用

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66871-w
Ghirardello, Mattia; Yruela, Inmaculada; Merino, Pedro; Sackstein, Robert; Sanz-Martínez, Ignacio; Hurtado-Guerrero, Ramón
发表日期：2025
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Harnessing Noncovalent π‑Type Interactions in Thiourea-Chloride Supramolecular Complexes: Toward the Asymmetric Dearomatization of Diazaheterocycles

利用硫脲-氯化物超分子复合物中的非共价π型相互作用：实现二氮杂环化合物的不对称脱芳构化

期刊:ACS Catalysis
影响因子:13.1
doi:10.1021/acscatal.5c04438
Velázquez, Marta; Elías-Rodríguez, Pilar; Tejero, Tomás; Fernández, Rosario; Merino, Pedro; Lassaletta, José M; Monge, David
发表日期：2025
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Loop engineering of enzymes to control their immobilization and ultimately fabricate more efficient heterogeneous biocatalysts

通过对酶进行环路工程改造，控制其固定化，最终制备出更高效的非均相生物催化剂。

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.70040
Zeballos, Nicoll; Ginés-Alcober, Irene; Macías-León, Javier; Andrés-Sanz, Daniel; González-Ramírez, Andrés Manuel; Sánchez-Costa, Mercedes; Merino, Pedro; Hurtado-Guerrero, Ramón; López-Gallego, Fernando
HTRF
发表日期：2025
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Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.

确定 FasL 是驱动 COVID-19 病理和致死性的关键宿主因素

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-024-01278-6
Albert Marie-Christine, Uranga-Murillo Iratxe, Arias Maykel, De Miguel Diego, Peña Natacha, Montinaro Antonella, Varanda Ana Beatriz, Theobald Sebastian J, Areso Itziar, Saggau Julia, Koch Manuel, Liccardi Gianmaria, Peltzer Nieves, Rybniker Jan, Hurtado-Guerrero Ramón, Merino Pedro, Monzón Marta, Badiola Juan J, Reindl-Schwaighofer Roman, Sanz-Pamplona Rebeca, Cebollada-Solanas Alberto, Megyesfalvi Zsolt, Dome Balazs, Secrier Maria, Hartmann Boris, Bergmann Michael, Pardo Julián, Walczak Henning
其它
发表日期：2024
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Rational Design of Dual-Domain Binding Inhibitors for N-Acetylgalactosamine Transferase 2 with Improved Selectivity over the T1 and T3 Isoforms

合理设计对N-乙酰半乳糖胺转移酶2具有更高选择性的双结构域结合抑制剂（针对T1和T3亚型）

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.4c00633
Compañón, Ismael; Ballard, Collin J; Lira-Navarrete, Erandi; Santos, Tanausú; Monaco, Serena; Muñoz-García, Juan C; Delso, Ignacio; Angulo, Jesus; Gerken, Thomas A; Schjoldager, Katrine T; Clausen, Henrik; Tejero, Tomás; Merino, Pedro; Corzana, Francisco; Hurtado-Guerrero, Ramon; Ghirardello, Mattia
发表日期：2024
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Molecular Recognition of GalNAc in Mucin-Type O-Glycosylation

粘蛋白型 O-糖基化中 GalNAc 的分子识别

期刊:Accounts of Chemical Research
影响因子:17.7
doi:10.1021/acs.accounts.2c00723
Sanz-Martinez, Ignacio; Pereira, Sandra; Merino, Pedro; Corzana, Francisco; Hurtado-Guerrero, Ramon
发表日期：2023
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