Pancreatic Cells Are Resistant to KRASQ61L Expression due to Hyperactive ERK/MAPK Signaling and Apoptosis Induction
胰腺细胞由于ERK/MAPK信号通路过度活跃和细胞凋亡诱导而对KRASQ61L表达具有抵抗性。
期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-25-0281
Burge, Rachel A; Bialousow, Lucas; McFall, Thomas; Bamonte, Logan; Johnson, Grayson; Smith, Merissa; Vaena, Silvia G; Comte-Walters, Susana; Ball, Lauren E; Berto, Stefano; O'Bryan, John P; Hobbs, G Aaron
凋亡
表观遗传
Apoptosis
信号转导
MAPK/ERK
细胞生物学
RAS